ANALYSIS OF ORGANOCHLORINE METABOLITES IN CRUDE EXTRACTS BY HIGH-RESOLUTION PHOTOPLATE MASS-SPECTROMETRY Academic Article

abstract

• High resolution photoplate mass spectrometry has been used to examine crude goat urine extracts to determine the fate of organochlorine xenobiotics in these animals. Using a direct introduction temperature controlled probe the crude urine extracts were analyzed and the presence of oxygenated metabolites of 4chlorobiphenyl and 4,4dichlorobiphenyl were confirmed in goats; analyses of urine extracts from goats injected with the commercial Aroclor mixtures 1254 and 5460 confirmed the formation of oxygenated penta, tetra and monochlorobiphenyl metabolites and an oxygenated dichloroterphenyl metabolite, respectively. This technique was particularly useful in the analysis of complex mixtures of metabolites. Copyright 1975 John Wiley & Sons, Ltd.

authors

• Safe, Stephen

published proceedings

• BIOMEDICAL MASS SPECTROMETRY

author list (cited authors)

• SAFE, S., PLATONOW, N., HUTZINGER, O., & JAMIESON, W. D.

citation count

• 13

complete list of authors

• SAFE, S||PLATONOW, N||HUTZINGER, O||JAMIESON, WD

publication date

• August 1975

publisher

• Wiley  Publisher

published in

• Biomedical mass spectrometry  Journal

Digital Object Identifier (DOI)

• 10.1002/bms.1200020407

start page

• 201

end page

• 203

volume

• 2

issue

• 4

URL

• http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1975AW39700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=dd60ee4408902e709853f976e23bc0ff