Assessment of factors related to carbohydrate intolerance III: Fasting HOMA (LB300)
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abstract
The fasting homeostatic model assessment (HOMA) is a gold standard in assessing insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a carbohydrate intolerance survey (CI) correlate to HOMA, an OGTT, body composition and/or markers of health. 108 women (31.613 yrs, 34.77% body fat, 25.34 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2hr OGTT. Pearson product correlations were performed to determine which factors correlated with HOMA. Results revealed significant correlations (p<0.05) in HOMA (1.511.1) to G120 (r=0.37), glucose AUC (r=0.30), glucose AUMC (r=0.32), Cmax (r=0.24), fasting insulin (r=0.99), G/I ratio (r=0.49), height (r=0.27), waist circumference (r=0.26), BMI (r=0.21), BMC (r=0.21), BMD (r=0.27), DEXA body fat (r=0.28), and BIA body fat (r=0.23). However, HOMA did not significantly correlate to any question on the CI or symptoms during the OGTT. Results indicate that HOMA is positively correlated to OGTT glucose values, fasting insulin, the G/I ratio, waist circumference, BMI, and %BF and negatively correlated with height, BMC, and BMD but not related to CI questionnaire items or CI symptoms during an OGTT. Grant Funding Source: Curves International, Inc. (Waco, TX)
