INTERACTION OF 6-METHYL-1,3,8-TRICHLORODIBENZOFURAN WITH TCDD-INDUCED VITAMIN A REDUCTION Academic Article

abstract

• 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) have been shown to inhibit TCDD-induced enzymeinduction both in rat and in cell culture. MCDF, alone or together with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), was administered to rats in order to investigate the ability of MCDF to reduce TCDD-induced vitamin A depletion. High doses of MCDF induced vitamin A-depletion, but no inhibitory effect on TCDD-induced depletion was seen in this experiment. 1989.

authors

• Safe, Stephen

published proceedings

• CHEMOSPHERE

author list (cited authors)

• WAERN, F., HANBERG, A., MANZOOR, E., SAFE, S., & AHLBORG, U. G.

citation count

• 2

complete list of authors

• Wærn, F||Hanberg, A||Manzoor, E||Safe, S||Ahlborg, UG

publication date

• January 1989

publisher

• Elsevier  Publisher

published in

• Chemosphere  Journal

keywords

• Agent Orange & Dioxin
• Complementary And Integrative Health
• Nutrition

Digital Object Identifier (DOI)

• 10.1016/0045-6535(89)90449-9

start page

• 1005

end page

• 1008

volume

• 19

issue

• 1-6

URL

• http://dx.doi.org/10.1016/0045-6535(89)90449-9