PHENIX: building new software for automated crystallographic structure determination.
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Structural genomics seeks to expand rapidly the number of protein structures in order to extract the maximum amount of information from genomic sequence databases. The advent of several large-scale projects worldwide leads to many new challenges in the field of crystallographic macromolecular structure determination. A novel software package called PHENIX (Python-based Hierarchical ENvironment for Integrated Xtallography) is therefore being developed. This new software will provide the necessary algorithms to proceed from reduced intensity data to a refined molecular model and to facilitate structure solution for both the novice and expert crystallographer.
Acta Crystallogr D Biol Crystallogr
author list (cited authors)
Adams, P. D., Grosse-Kunstleve, R. W., Hung, L. W., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., ... Terwilliger, T. C
complete list of authors
Adams, Paul D||Grosse-Kunstleve, Ralf W||Hung, Li Wei||Ioerger, Thomas R||McCoy, Airlie J||Moriarty, Nigel W||Read, Randy J||Sacchettini, James C||Sauter, Nicholas K||Terwilliger, Thomas C