Syntenic conservation between humans and cattle. I. Human chromosome 9. Academic Article

abstract

• Bovine X hamster hybrid somatic cells have been used to investigate the syntenic relationship of nine loci in the bovine that have homologous loci on human chromosome 9. Six loci, ALDH1, ALDOB, C5, GGTB2, GSN, and ITIL, were assigned to the previously identified bovine syntenic group U18 represented by ACO1, whereas the other three loci, ABL, ASS, and GRP78, mapped to a new, previously unidentified autosomal syntenic group. Additionally, a secondary locus, ABLL, which cross-hybridized with the ABL probe, was mapped to bovine syntenic group U1 with the HSA 1 loci PGD and ENO1. The results predict that ACO1 will map proximal to ALDH1; GRP78 distal to ITIL and C5; GSN proximal to AK1, ABL, and ASS on HSA 9; GRP78 to MMU 2; and ITIL and GSN to MMU 4.

authors

• Threadgill, David
• Womack, James

published proceedings

• Genomics

author list (cited authors)

• Threadgill, D. W., & Womack, J. E.

citation count

• 35

complete list of authors

• Threadgill, DW||Womack, JE

publication date

• September 1990

publisher

• Elsevier  Publisher

published in

• Genomics  Journal

keywords

• Animals
• Base Sequence
• Blotting, Southern
• Cattle
• Chromosome Mapping
• Chromosomes, Human, Pair 9
• Cricetinae
• DNA
• DNA Probes
• Endoplasmic Reticulum Chaperone Bip
• Humans
• Hybrid Cells
• Mice
• Sequence Homology, Nucleic Acid

PubMed Central ID

• 2081596

Digital Object Identifier (DOI)

• 10.1016/0888-7543(90)90221-f

start page

• 22

end page

• 28

volume

• 8

issue

• 1

URL

• http://dx.doi.org/10.1016/0888-7543(90)90221-f