Gastrointestinal transit time is faster in Beagle dogs compared to cats.
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OBJECTIVE: To characterize gastrointestinal transit times (GITTs) and pH in dogs, and to compare to data recently described for cats. ANIMALS: 7 healthy, colony-housed Beagles. PROCEDURES: The GITTs and pH were measured using a continuous pH monitoring system. For the first period (prefeeding), food was withheld for 20 hours followed by pH capsule administration. Five hours after capsule administration, dogs were offered 75% of their historical daily caloric intake for 1 hour. For the second period (postfeeding), food was withheld for 24 hours. Dogs were allowed 1 hour to eat, followed by capsule administration. Both periods were repeated 3 times. The GITTs and pH were compared to published feline data. RESULTS: The mean SD transit times in dogs for the pre- and postfeeding periods, respectively, were esophageal, 3 5 minutes and 13 37 minutes; gastric, 31 60 minutes and 829 249 minutes; and intestinal, 795 444 minutes and 830 368 minutes. The mean SD gastrointestinal pH in dogs for the pre- and postfeeding periods, respectively, were esophageal, 6.6 0.6 and 5.7 1.0; gastric, 3.0 1.4 and 1.8 0.3; intestinal, 7.9 0.3 and 7.7 0.6; first-hour small intestinal, 7.6 0.5 and 7.1 0.4; and last-hour large intestinal, 7.9 0.6 and 7.7 1.0. The first-hour small intestinal pH and total transit times varied between dogs and cats depending on feed period (P = .002 and P = .04, respectively). Post hoc analysis revealed significantly shorter total transit times in dogs prefeeding (P = .005; mean SD for cats, 2,441 1,359 minutes; for dogs, 828 439 minutes) and postfeeding (P = .03; mean SD for cats, 3,009 1,220 minutes; for dogs, 1,671 513 minutes). Total transit time for dogs was also shorter pre- versus postfeeding (P = .003). CLINICAL RELEVANCE: GITT is faster in Beagles compared to cats, but gastrointestinal pH are similar when fed the same diet.
author list (cited authors)
Tolbert, M. K., Telles, N. J., Simon, B. T., Scallan, E. M., Price, J. M., Gould, E. N., ... Kathrani, A.
complete list of authors
Tolbert, M Katherine||Telles, Naila J||Simon, Bradley T||Scallan, Elizabeth M||Price, Joshua M||Gould, Emily N||Papich, Mark G||Lidbury, Jonathan A||Steiner, Jörg M||Kathrani, Aarti