Phytocomplexes from liquorice (Glycyrrhiza glabra L.) leaves Chemical characterization and evaluation of their antioxidant, anti-genotoxic and anti-inflammatory activity
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Three extracts of different polarities of Glycyrrhiza glabra L. leaves were characterized and evaluated for their antioxidant, anti-genotoxic and anti-inflammatory activity. In total, thirty components have been identified and quantified through the use of liquid chromatography (LC) with ultraviolet-visible diode-array-detector (UV-vis-DAD) and mass spectrometry (MS). The main components belong to the polyphenols family, being flavonoid and dihydrostilbene derivatives. The extracts have been investigated for their antioxidant, anti-genotoxic and anti-inflammatory activities, which are fundamental requirements of efficacious chemo-preventive agents. The ethyl acetate extract proved to be the most valuable, evidently for the conspicuous presence of several polyphenols, namely flavonoids and dihydrostilbenes.
author list (cited authors)
Siracusa, L., Saija, A., Cristani, M., Cimino, F., D'Arrigo, M., Trombetta, D., Rao, F., & Ruberto, G.
complete list of authors
Siracusa, Laura||Saija, Antonella||Cristani, Mariateresa||Cimino, Francesco||D'Arrigo, Manuela||Trombetta, Domenico||Rao, Felice||Ruberto, Giuseppe