HR job title
- Professor
- Contact Info
- 1 979 458 4725
- ORCiD
- 0000-0002-9146-3339
Dindot, Scott Associate Professor
Positions
- Associate Professor, Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences
Research Areas
- Overview
- Publications
- Research
- Teaching
- Works By Students
- Background
- Contact
- Other
- View All
Overview
Publications
selected publications
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academic article
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Dindot, S. V., Christian, S., Murphy, W. J., Berent, A., Panagoulias, J., Schlafer, A., ... FIRE Consortium.
(2023).
An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript. Science Translational Medicine.
15(688), eabf4077.
-
Beitnere, U., Vilanova-Cuevas, B., Christian, S. G., Taylor, C., Berg, E. L., Copping, N. A., ... Segal, D. J.
(2023).
Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome. 8(1), e0060822-e00622.
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St Jean, S. C., Jortner, B. S., Doan, R. N., Dindot, S. V., Johnson, G. S., Bullock, G., ... Porter, B. F.
(2022).
Pathologic characterization of canine multiple system degeneration in the Ibizan hound. Veterinary Pathology.
59(1), 132-137.
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Born, H. A., Martinez, L. A., Levine, A. T., Harris, S. E., Mehra, S., Lee, W. L., ... Anderson, A. E.
(2021).
Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome. eNeuro.
8(2), eneuro.0345-eneu20.2020.
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Kelly, E., Meng, F., Fujita, H., Morgado, F., Kazemi, Y., Rice, L. C., ... Tsai, P. T.
(2020).
Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits. Nature Neuroscience.
23(9), 1102-1110.
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Dodge, A., Peters, M. M., Greene, H. E., Dietrick, C., Botelho, R., Chung, D., ... Nash, K. R.
(2020).
Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion. Autism Research: official journal of the International Society for Autism Research.
13(3), 397-409.
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Salazar-Medina, A. J., Velazquez-Contreras, E. F., Sugich-Miranda, R., Santacruz, H., Navarro, R. E., Rocha-Alonzo, F., ... Criscitiello, M. F.
(2020).
Immune response of human cultured cells towards macrocyclic Fe2PO and Fe2PC bioactive cyclophane complexes. 8, e8956-e8956.
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Berg, E. L., Pride, M. C., Petkova, S. P., Lee, R. D., Copping, N. A., Shen, Y., ... Silverman, J. L.
(2020).
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome. Translational Psychiatry.
10(1), 39.
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Dindot, S. V., Doan, R. N., Kuskie, K. R., Hillman, P. R., Whitfield, C. M., McQueen, C. M., ... Cohen, N. D.
(2018).
Postnatal changes in epigenetic modifications of neutrophils of foals are associated with increased ROS function and regulation of neutrophil function. Developmental and Comparative Immunology.
87, 182-187.
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Quist, E. M., Doan, R., Pool, R. R., Porter, B. F., Bannasch, D. L., & Dindot, S. V.
(2018).
Identification of a Candidate Mutation in the COL1A2 Gene of a Chow Chow With Osteogenesis Imperfecta. JOURNAL OF HEREDITY.
109(3), 308-314.
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Hillman, P. R., Christian, S., Doan, R., Cohen, N. D., Konganti, K., Douglas, K., ... Dindot, S. V.
(2017).
Genomic imprinting does not reduce the dosage of UBE3A in neurons. Epigenetics and Chromatin.
10(1), 27.
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Copping, N. A., Christian, S., Ritter, D. J., Islam, M. S., Buscher, N., Zolkowska, D., ... Dindot, S. V.
(2017).
Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome. Human Molecular Genetics.
26(20), 3995-4010.
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Alves, B., Cardoso, R. C., Doan, R., Zhang, Y., Dindot, S. V., Williams, G. L., & Amstalden, M.
(2017).
Nutritional programming of accelerated puberty in heifers: alterations in DNA methylation in the arcuate nucleus. Biology of Reproduction.
96(1), 174-184.
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McQueen, C. M., Whitfield-Cargile, C. M., Konganti, K., Blodgett, G. P., Dindot, S. V., & Cohen, N. D.
(2016).
TRPM2 SNP genotype previously associated with susceptibility to Rhodococcus equi pneumonia in Quarter Horse foals displays differential gene expression identified using RNA-Seq. BMC GENOMICS.
17(1), 993.
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McQueen, C. M., Dindot, S. V., Foster, M. J., & Cohen, N. D.
(2015).
Genetic Susceptibility to Rhodococcus equi. Journal of Veterinary Internal Medicine (JVIM).
29(6), 1648-1659.
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Gershwin, L. J., Van Eenennaam, A. L., Anderson, M. L., McEligot, H. A., Shao, M. X., Toaff-Rosenstein, R., ... Bovine Respiratory Disease Complex Coordinated Agricultural Project Research Team.
(2015).
Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex. 10(11), e0142479-e0142479.
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Chisholm, N. C., Henderson, M. L., Selvamani, A., Park, M. J., Dindot, S., Miranda, R. C., & Sohrabji, F.
(2015).
Histone methylation patterns in astrocytes are influenced by age following ischemia. Epigenetics.
10(2), 142-152.
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Ghaffari, N., Sanchez-Flores, A., Doan, R., Garcia-Orozco, K. D., Chen, P. L., Ochoa-Leyva, A., ... Criscitiello, M. F.
(2014).
Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture. Scientific Reports.
4(1), 7081.
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McQueen, C. M., Doan, R., Dindot, S. V., Bourquin, J. R., Zlatev, Z. Z., Chaffin, M. K., ... Cohen, N. D.
(2014).
Identification of genomic loci associated with Rhodococcus equi susceptibility in foals. PLoS ONE.
9(6), e98710-e98710.
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Dindot, S. V., & Cohen, N. D.
(2013).
Epigenetic Regulation of Gene Expression: Emerging Applications for Horses. Journal of Equine Veterinary Science.
33(5), 288-294.
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Balaraman, S., Doan, R., Dindot, S., & Miranda, R.
(2013).
Epigenetic Regulation of MicroRNAs in Fetal Neural Stem Cells: Uncovering Novel Mechanisms of Ethanol Teratology. 97(5), 305-305.
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Wang, J., Wu, Z., Li, D., Li, N., Dindot, S. V., Satterfield, M. C., Bazer, F. W., & Wu, G.
(2012).
Nutrition, epigenetics, and metabolic syndrome. Antioxidants and Redox Signaling.
17(2), 282-301.
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Doan, R., Cohen, N., Harrington, J., Veazey, K., Juras, R., Cothran, G., ... Dindot, S. V.
(2012).
Identification of copy number variants in horses. Genome Research.
22(5), 899-907.
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Doan, R., Cohen, N. D., Sawyer, J., Ghaffari, N., Johnson, C. D., & Dindot, S. V.
(2012).
Whole-genome sequencing and genetic variant analysis of a Quarter Horse mare. BMC GENOMICS.
13(1), 78.
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Dindot, S., Piccolo, P., Grove, N., Palmer, D., & Brunetti-Pierri, N.
(2011).
Intrathecal injection of helper-dependent adenoviral vectors results in long-term transgene expression in neuroependymal cells and neurons. Human Gene Therapy.
22(6), 745-751.
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Dindot, S. V., Person, R., Strivens, M., Garcia, R., & Beaudet, A. L.
(2009).
Epigenetic profiling at mouse imprinted gene clusters reveals novel epigenetic and genetic features at differentially methylated regions. Genome Research.
19(8), 1374-1383.
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Dindot, S. V., Antalffy, B. A., Bhattacharjee, M. B., & Beaudet, A. L.
(2008).
The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Human Molecular Genetics.
17(1), 111-118.
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Dindot, S. V., Kent, K. C., Evers, B., Loskutoff, N., Womack, J., & Piedrahita, J. A.
(2004).
Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine. MAMMALIAN GENOME.
15(12), 966-974.
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Dindot, S. V., Farin, P. W., Farin, C. E., Romano, J., Walker, S., Long, C., & Piedrahita, J. A.
(2004).
Epigenetic and genomic imprinting analysis in nuclear transfer derived Bos gaurus/Bos taurus hybrid fetuses. Biology of Reproduction.
71(2), 470-478.
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Piedrahita, J. A., Mir, B., Dindot, S., & Walker, S.
(2004).
Somatic cell cloning: the ultimate form of nuclear reprogramming?. 15(5), 1140-1144.
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Dindot, S. V., Farin, P., Farin, C., Alexander, J., Crosier, E., Walker, S., Long, C., & Piedrahita, J. A.
(2004).
35ANALYSIS OF EPIGENETIC MODIFICATIONS AND GENOMIC IMPRINTING IN NUCLEAR TRANSFER DERIVED BOS GAURUSB. TAURUS CONCEPTI. Reproduction, Fertility and Development.
16(2), 140-140.
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Archer, G. S., Dindot, S., Friend, T. H., Walker, S., Zaunbrecher, G., Lawhorn, B., & Piedrahita, J. A.
(2003).
Hierarchical phenotypic and epigenetic variation in cloned swine. Biology of Reproduction.
69(2), 430-436.
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Dindot, S. V., Christian, S., Murphy, W. J., Berent, A., Panagoulias, J., Schlafer, A., ... FIRE Consortium.
(2023).
An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript. Science Translational Medicine.
15(688), eabf4077.
-
conference paper
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Piccolo, P., Dindot, S., Grove, N., Palmer, D., & Brunetti-Pierri, N.
(2010).
Intrathecal injection of HDAd vectors results in long-term transgene expression in neuroepithelial cells and neurons. Human Gene Therapy.
1395-1395.
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Piccolo, P., Dindot, S., Grove, N., Palmer, D., & Brunetti-Pierri, N.
(2010).
Intrathecal injection of HDAd vectors results in long-term transgene expression in neuroepithelial cells and neurons. Human Gene Therapy.
1395-1395.
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institutional repository document
-
Beitnere, U., Vilanova-Cuevas, B., Christian, S. G., Taylor, C., Berg, E. L., Copping, N. A., ... Segal, D. J.
(2022).
Unique features of the gut microbiome characterized in animal models of Angelman Syndrome
-
Dindot, S. V., Christian, S., Murphy, W. J., Berent, A., Panagoulias, J., Schlafer, A., ... consortium, t. F.
(2021).
Development of an ASO therapy for Angelman syndrome by targeting an evolutionarily conserved region at the start of the UBE3A-AS transcript
-
Ghaffari, N., Sanchez-Flores, A., Doan, R., Garcia-Orozco, K. D., Chen, P. L., Ochoa-Leyva, A., ... Criscitiello, M. F.
(2014).
Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture. Scientific Reports.
-
Dindot, S. V.
(2004).
The development of a bovine interspecies model for the analysis of genomic imprinting in normal and nuclear transfer derived fetuses
-
Beitnere, U., Vilanova-Cuevas, B., Christian, S. G., Taylor, C., Berg, E. L., Copping, N. A., ... Segal, D. J.
(2022).
Unique features of the gut microbiome characterized in animal models of Angelman Syndrome
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patent
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Dindot, S. V.
(2021).
Angelman syndrome antisense treatment
-
Dindot, S. V.
(2021).
Angelman syndrome antisense treatment
Research
co-principal investigator on
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- BIMS320 Biomedical Genetics Instructor
- BIMS421 Advanced Human Genetics Instructor
- BIMS491 Hnr-research Instructor
- GENE320 Biomedical Genetics Instructor
- GENE421 Advanced Human Genetics Instructor
- GENE691 Research Instructor
- MSCI691 Research Credit: Medical Sci Instructor
- VTMI689 Sptp: Adv Human Genetics Instructor
- VTMI691 Research Instructor
- VTPB485 Directed Studies Instructor
Works By Students
chaired theses and dissertations
-
Benjamin, Jade Marie (2017-07). Understanding the Imprinting Mechanism of UBE3A for Therapeutic Intervention.
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Doan, Ryan (2013-06). The Identification and Characterization of Copy Number Variants in the Bovine Genome.
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Hillman, Paul Randolph (2015-05). Analysis of Genomic Imprinting of UBE3A in Neurons.
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McQueen, Cole M (2015-12). Investigating Genetic Susceptibility to Rhodococcus equi.
Background
education and training
- Ph.D. in Genetics, Texas A&M University - (College Station, Texas, United States) 2003
- B.S. in Molecular and Cell Biology, Texas A&M University - (College Station, Texas, United States) 1999
- Baylor College of Medicine - (Houston, Texas, United States) , Postdoctoral Training 2008
awards and honors
Contact
first name
- Scott
has last name
- Dindot
mailing address
-
Texas A&M University
Vet Med Pathobiology
4467 TAMU
College Station, TX 77843-4467
USA
Other
In the News
- From parent advocate to nonprofit chief science officer, to biotherapeutic company cofounder - A personal journey through drug development for Angelman Syndrome News Release
- GeneTx and Ultragenyx Announce Positive Interim Phase 1/2 Data on Investigational GTX-102 Demonstrating Improvement in Patients with Angelman Syndrome News Release
- GeneTx and Ultragenyx Announce Presentation of Phase 1/2 Data on Investigational GTX-102 in Patients with Angelman Syndrome News Release
- sdindot@tamu.edu