Associative Learning and Memory for an Antinociceptive Response in the Spinalized Rat Academic Article

abstract

• Prior research suggests that associative and memorial processes can modulate the activation of the endogenous antinociceptive systems. It has been generally assumed that forebrain systems play an essential role in mediating the impact of these processes. The present experiments explored whether the behavioral effects indicative of associative and memorial processes can be obtained in spinalized rats. Experiment 1 demonstrated that a conditioned nonopioid antinociception can be established after rats have experienced a spinal transection at the level of the 2nd thoracic vertebrae. Experiment 2 showed that a postshock distractor can speed the decay of shock-induced antinociception in the spinalized rat. These findings suggest that the circuitry needed to obtain associative and memorylike effects is present within the spinal cord.

authors

• Grau, James
• Meagher, Mary

published proceedings

• Behavioral Neuroscience

altmetric score

• 1

author list (cited authors)

• Grau, J. W., Salinas, J. A., Illich, P. A., & Meagher, M. W.

citation count

• 39

complete list of authors

• Grau, James W||Salinas, Juan A||Illich, Paul A||Meagher, Mary W

publication date

• January 1990

publisher

• American Psychological Association (APA)  Publisher

published in

• BEHAVIORAL NEUROSCIENCE  Journal

keywords

• Animals
• Arousal
• Association Learning
• Attention
• Conditioning, Classical
• Electroshock
• Learning
• Male
• Memory
• Mental Recall
• Neurosciences
• Nociceptors
• Rats
• Rats, Inbred Strains
• Reaction Time
• Receptors, Opioid
• Spinal Cord

Digital Object Identifier (DOI)

• 10.1037/0735-7044.104.3.489

start page

• 489

end page

• 494

volume

• 104

issue

• 3

URL

• http://dx.doi.org/10.1037/0735-7044.104.3.489