Conditioned changes in pain reactivity: II. In search of the elusive phenomenon of conditioned hyperalgesia. Academic Article

abstract

• Previous research suggests that a stimulus that has been paired with an aversive event can elicit either an increase (hyperalgesia) or decrease (hypoalgesia) in pain reactivity in rats. Attempts have recently been made to isolate the variables that determine the direction of the conditioned response. Very little evidence has been found for conditioned hyperalgesia when a spinally mediated measure of pain reactivity (the tail-flick test) was used. In the present study, the impact of a conditioned stimulus was assessed using a procedure modeled after one in which conditioned hyperalgesia was obtained with the tail-flick test (Davis & Hendersen, 1985, Experiment 4). With this training paradigm, a discrete conditioned stimulus was found to elicit hypoalgesia but not hyperalgesia.

authors

• Grau, James

published proceedings

• Behav Neurosci

author list (cited authors)

• Illich, P. A., Salinas, J. A., & Grau, J. W.

citation count

• 5

complete list of authors

• Illich, PA||Salinas, JA||Grau, JW

publication date

• June 1991

publisher

• American Psychological Association (APA)  Publisher

keywords

• Acoustic Stimulation
• Animals
• Behavior, Animal
• Conditioning, Classical
• Electroshock
• Humans
• Hyperalgesia
• Infant
• Male
• Pain
• Rats
• Rats, Inbred Strains
• Reaction Time

Digital Object Identifier (DOI)

• 10.1037//0735-7044.105.3.478

start page

• 478

end page

• 481

volume

• 105

issue

• 3

URL

• http://dx.doi.org/10.1037/0735-7044.105.3.478