selected publications academic article Logan, S. M., Ruest, L. B., Benson, M. D., & Svoboda, K. (2020). Extracellular Matrix in Secondary Palate Development. ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY. 303(6), 1543-1556. Fritz, K. R., Zhang, Y., & Ruest, L. B (2019). Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract. Developmental Dynamics. 248(9), 795-812. Ibrahim, I., Serrano, M. J., Ruest, L. B., & Svoboda, K. (2017). Biglycan and Decorin Expression and Distribution in Palatal Adhesion. Journal of Dental Research. 96(12), 1445-1450. Ruest, L. B., Ranjbaran, H., Tong, E. J., Svoboda, K., & Feng, J. Q. (2016). Activation of Receptor Activator of Nuclear Factor-B Ligand and Matrix Metalloproteinase Production in Periodontal Fibroblasts by Endothelin Signaling. J Periodontol. 87(1), e1-e8. Wang, X., Wang, J., Liu, Y., Yuan, B., Ruest, L. B., Feng, J. Q., & Qin, C. (2015). The specific role of FAM20C in dentinogenesis. Journal of Dental Research. 94(2), 330-336. Zhang, Y., Knutsen, G. R., Brown, M. D., & Ruest, L. B (2013). Control of endothelin-a receptor expression by progesterone is enhanced by synergy with Gata2. Molecular Endocrinology. 27(6), 892-908. Gibson, M. P., Zhu, Q., Wang, S., Liu, Q., Liu, Y., Wang, X., ... Lu, Y. (2013). The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis. Journal of Biological Chemistry. 288(10), 7204-7214. Yu, W., Zhang, Y., Ruest, L. B., & Svoboda, K. (2013). Analysis of Snail1 function and regulation by Twist1 in palatal fusion. Front Physiol. 4, 12. Zhang, Y., & Ruest, L. B (2012). Analysis of neural crest cell fate during cardiovascular development using Cre-activated lacZ/β-galactosidase staining. Methods Mol Biol. 843, 125-138. Zhang, Y., Blackwell, E. L., McKnight, M. T., Knutsen, G. R., Vu, W. T., & Ruest, L. B (2012). Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2. Developmental Dynamics. 241(5), 924-940. Green, M. L., Singh, A. V., Ruest, L. B., Pisano, M. M., Prough, R. A., & Knudsen, T. B (2011). Differential programming of p53-deficient embryonic cells during rotenone block. Toxicology. 290(1), 31-41. Yu, W., Serrano, M., Miguel, S. S., Ruest, L. B., & Svoboda, K. (2009). Cleft lip and palate genetics and application in early embryological development. Indian Journal of Plastic Surgery. 42 Suppl(3), S35-S50. Yu, W., Ruest, L., & Svoboda, K. (2009). Regulation of epithelial-mesenchymal transition in palatal fusion. EXPERIMENTAL BIOLOGY AND MEDICINE. 234(5), 483-491. Ruest, L., & Clouthier, D. E (2009). Elucidating timing and function of endothelin-A receptor signaling during craniofacial development using neural crest cell-specific gene deletion and receptor antagonism. Dev Biol. 328(1), 94-108. Datta, S., Turner, D., Singh, R., Ruest, L. B., Pierce, W. M., & Knudsen, T. B (2008). Fetal alcohol syndrome (FAS) in C57BL/6 mice detected through proteomics screening of the amniotic fluid. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY. 82(4), 177-186. Abe, M., Ruest, L., & Clouthier, D. E (2007). Fate of cranial neural crest cells during craniofacial development in endothelin-A receptor-deficient mice. The International Journal of Developmental Biology. 51(2), 97-105. Ruest, L., Kedzierski, R., Yanagisawa, M., & Clouthier, D. E (2005). Deletion of the endothelin-A receptor gene within the developing mandible. Cell Tissue Res. 319(3), 447-453. Ruest, L., Xiang, X., Lim, K., Levi, G., & Clouthier, D. E (2004). Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. 131(18), 4413-4423. Pan, J., Ruest, L., Xu, S., & Wang, E (2004). Immuno-characterization of the switch of peptide elongation factors eEF1A-1/EF-1alpha and eEF1A-2/S1 in the central nervous system during mouse development. Brain Res Dev Brain Res. 149(1), 1-8. Ruest, L., Hammer, R. E., Yanagisawa, M., & Clouthier, D. E (2003). Dlx5/6-enhancer directed expression of Cre recombinase in the pharyngeal arches and brain. Genesis: The Journal of Genetics and Development. 37(4), 188-194. Ruest, L., Dager, M., Yanagisawa, H., Charité, J., Hammer, R. E., Olson, E. N., Yanagisawa, M., & Clouthier, D. E. (2003). dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Dev Biol. 257(2), 263-277. Ruest, L., Khalyfa, A., & Wang, E (2002). Development-dependent disappearance of caspase-3 in skeletal muscle is post-transcriptionally regulated. J Cell Biochem. 86(1), 21-28. Syed, N. A., Horner, K. N., Misra, V., & Khandelwal, R. L (2002). Different cellular localization, translocation, and insulin-induced phosphorylation of PKBalpha in HepG2 cells and hepatocytes. J Cell Biochem. 86(1), 118-127. Ruest, L., Marcotte, R., & Wang, E (2002). Peptide elongation factor eEF1A-2/S1 expression in cultured differentiated myotubes and its protective effect against caspase-3-mediated apoptosis. Journal of Biological Chemistry. 277(7), 5418-5425. conference paper Ruest, L. B., Svoboda, K., & Opperman, L. A. (2017). Student Survey Results on the Integration of Active Learning Exercises in a Dental Education Self-Learning Setting. The FASEB Journal. Ruest, L. B., Svoboda, K., & Opperman, L. A. (2016). Integration of Active-Learning Activity Increased Short-Term and Long-Term Retention in a Self-Learning Setting. The FASEB Journal. Ruest, L. B., Svoboda, K., & Opperman, L. A. (2016). Integration of Active-Learning Activity Increased Short-Term and Long-Term Retention in a Self-Learning Setting. The FASEB Journal. Ruest, L. B., Svoboda, K., & Opperman, L. A. (2016). Integration of Active-Learning Activity Increased Short-Term and Long-Term Retention in a Self-Learning Setting. The FASEB Journal. Svoboda, K., Ibrahim, I., Serrano, M. J., & Ruest, L (2016). TGF beta Signaling Regulates Decorin and Biglycan Expression and Distribution During Murine Palatal Fusion. The FASEB Journal. Svoboda, K., Ibrahim, I., Serrano, M. J., & Ruest, L (2016). TGF beta Signaling Regulates Decorin and Biglycan Expression and Distribution During Murine Palatal Fusion. The FASEB Journal. Svoboda, K., Ibrahim, I., Serrano, M. J., & Ruest, L (2016). TGF beta Signaling Regulates Decorin and Biglycan Expression and Distribution During Murine Palatal Fusion. The FASEB Journal. Ruest, L. B., Ranjbaran, H., Tong, E., San Miguel, S., & Svoboda, K (2015). Activation of RANKL and MMP Production by Endothelin Signaling in Cultured Periodontal Fibroblasts. The FASEB Journal. Svoboda, K., Ruest, L., Spears, R., Roeche, D., & Opperman, L (2015). Subject Specific Cross Word Puzzles Were Effective Active Learning Tools. The FASEB Journal. Ruest, L. B., Zhang, Y., Blackwell, E. L., McKnight, M. T., & Knutsen, G. R (2012). TWISTing a Hand on the mandible. The FASEB Journal.
teaching activities DDDS603 Human Struc Func & Disease Ii Instructor OBIO605 Mammalian Physiology Instructor OBIO630 Growth Mechanisms Of Dev Instructor OBIO631 Adv Hum Cran Dev Cran Anomal Instructor OBIO671 Applied Medical Physiology Instructor OBIO675 Curr Topics Biomed Sciences I Instructor OBIO676 Curr Topics Biomed Sciences Ii Instructor OBIO677 Directed Readings I Instructor OBIO678 Directed Readings Ii Instructor OBIO679 Directed Readings Iii Instructor OBIO687 Research Special Problems I Instructor OBIO688 Research Special Problems Ii Instructor OBIO691 Research Instructor
education and training Ph.D. in Molecular and Cellular Biology, McGill University - (Montreal, Quebec, Canada) 2002 B.Sc. in Biology/Microbiology, Universite de Sherbrooke - (Sherbrooke, Quebec, Canada) 1996 University of Louisville - (Louisville, Kentucky, United States) , Postdoctoral Training 2006
mailing address Texas A&M University College of Dentistry Biomedical Sciences 3302 Gaston Avenue Dallas, TX 75246 USA