Peptides and methods for inhibiting Galpha protein signaling Patent uri icon


  • Permeable Switch Region I and II peptides in the range of 9 to 25 amino acid residues in length are provided for specifically inhibiting signaling through G subunits. In addition, compositions and methods for inhibiting platelet aggregation and 11b3 integrin activation using the Switch Region I and II peptides are provided.

author list (cited authors)

  • Breton, G. L., Huang, J., Srinivasan, S., & Khasawneh, F.

publication date

  • January 2013