COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?
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The ongoing Corona virus (COVID-19) pandemic has witnessed global political responses of unimaginable proportions. Many nations have implemented lockdowns that involve mandating citizens not to leave their residences for non-essential work. The Indian government has taken appropriate and commendable steps to curtail the community spread of COVID-19. While this may be extremely beneficial, this perspective discusses the other reasons why COVID-19 may have a lesser impact on India. We analyze the current pattern of SARS-CoV-2 transmission, testing, and mortality in India with an emphasis on the importance of mortality as a marker of the clinical relevance of COVID-19 disease. We also analyze the environmental and biological factors which may lessen the impact of COVID-19 in India. The importance of cross-immunity, innate immune responses, ACE polymorphism, and viral genetic mutations are discussed.
author list (cited authors)
Chakrabarti, S. S., Kaur, U., Banerjee, A., Ganguly, U., Banerjee, T., Saha, S., ... Chakrabarti, S
complete list of authors
Chakrabarti, Sankha Shubhra||Kaur, Upinder||Banerjee, Anindita||Ganguly, Upasana||Banerjee, Tuhina||Saha, Sarama||Parashar, Gaurav||Prasad, Suvarna||Chakrabarti, Suddhachitta||Mittal, Amit||Agrawal, Bimal Kumar||Rawal, Ravindra Kumar||Zhao, Robert Chunhua||Gambhir, Indrajeet Singh||Khanna, Rahul||Shetty, Ashok K||Jin, Kunlin||Chakrabarti, Sasanka