NOVEL BIO-SYNTHETIC GRAFT FOR TRACHEAL RECONSTRUCTION IN PEDIATRIC PATIENTS WITH CONGENITAL TRACHEAL STENOSIS: IN VITRO STUDIES OF AXIAL, AND BENDING BIOMECHANICS Conference Paper uri icon

abstract

  • Congenital Tracheal Stenosis (CTS) is a rare birth defect requiring surgical interventions when it affects more than 30% of the trachea. Slide tracheoplasty, the current standard of care, is associated with reinterventions including the need for intraluminal stenting leading to increased airway infections. We propose a novel Bio-Synthetic Graft for long segment tracheal reconstructions in CTS patients. Preliminary bench performance testing, using lamb tracheas, shows that the Bio-Synthetic Graft reconstructed tracheas have comparable radial, axial and bending stiffness in hyperextension to healthy tracheas and resist collapse when subjected to bending in flexion. These results suggest that Bio-Synthetic Graft could be a promising alternative to existing solutions for long segment CTS.

name of conference

  • 2019 Design of Medical Devices Conference

published proceedings

  • 2019 DESIGN OF MEDICAL DEVICES CONFERENCE

author list (cited authors)

  • Karkhanis, T., Zafar, F., Juarez, B., Morales, D., & Haridas, B.

citation count

  • 0

complete list of authors

  • Karkhanis, Teja||Zafar, Farhan||Juarez, Brian||Morales, David Luis-Simon||Haridas, Balakrishna

publication date

  • April 2019