Fluorous phase-transfer activation of catalysts : application of a new rate-enhancement strategy to alkene metathesis Academic Article uri icon

abstract

  • Reactions of the bis(pyridine) complex (H2IMes)(Py)2(Cl)2Ru(=CHPh) and fluorous phosphines P(CH2CH2R(fn))3 (n = a, 6; b, 8; c, 10; R(fn) = (CF2)(n-1)CF3) give (H2IMes)(P(CH2CH2R(fn))3)(Cl)2Ru(=CHPh) (2a-c, 64-73%), which are analogs of Grubbs' second generation catalyst and effective alkene metathesis catalysts under organic monophasic and fluorous/organic biphasic conditions. The latter give rate accelerations, which are believed to arise from phase transfer of the dissociated fluorous phosphine.

altmetric score

  • 3

author list (cited authors)

  • CorrĂȘa da Costa, R., & Gladysz, J. A.

citation count

  • 44

publication date

  • June 2006