A NOVEL METHOD FOR 3-D SEGMENTATION AND VOLUME ESTIMATION OF BRAIN COMPARTMENTS FROM MRI
Additional Document Info
A 3-D, multiple intensity, region-growing technique is developed to segment the voxels into regions corresponding to purely white or gray matter. These voxel intensities are used to characterize the pure white and gray matter. There remains a shell of voxels between the white and gray regions. Each voxel in this shell contains a mixture of white and gray matter. A least-squares vector estimator is then used to determine the fraction of white and gray matter in each of these voxels. From these data the gray/white (g/w) ratio is calculated. An initial application of this method was able to detect g/w ratios in AIDS patients. The power of this technique lies in its ability to quantitate small changes globally affecting a volume.
name of conference
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991