Adoptive Cell Transfer: Is it a Promising Immunotherapy for Colorectal Cancer? Academic Article

abstract

• The last decade has witnessed significant advances in the adoptive cell transfer (ACT) technique, which has been appreciated as one of the most promising treatments for patients with cancer. Utilization of ACT can enhance the function of the immune system or improve the specificity and persistence of transferred cells. Various immune cells including T lymphocytes, natural killer cells, dendritic cells, and even stem cells can be used in the ACT despite their different functional mechanisms. Colorectal cancer (CRC) is among the most common malignancies and causes millions of deaths worldwide every year. In this review, we discuss the status and perspective of the ACT in the treatment of CRC.

authors

• Song, Jianxun

published proceedings

• Theranostics

altmetric score

• 0.25

author list (cited authors)

• Fan, J., Shang, D., Han, B., Song, J., Chen, H., & Yang, J.

citation count

• 40

complete list of authors

• Fan, Jiaqiao||Shang, Dong||Han, Bing||Song, Jianxun||Chen, Hailong||Yang, Jin-Ming

publication date

• January 2018

publisher

• Ivyspring International Publisher  Publisher

published in

• Theranostics  Journal

keywords

• Adoptive Cell Transfer
• Adoptive Transfer
• Biomedical Research
• Colorectal Cancer
• Colorectal Neoplasms
• Dendritic Cells
• Humans
• Immunotherapy
• Killer Cells, Natural
• Stem Cells
• T-Lymphocytes

Digital Object Identifier (DOI)

• 10.7150/thno.29035

start page

• 5784

end page

• 5800

volume

• 8

issue

• 20

URL

• http://dx.doi.org/10.7150/thno.29035