Monitoring Lung Mechanics during Mechanical Ventilation using Machine Learning Algorithms. Academic Article uri icon


  • Evaluation of lung mechanics is the primary component for designing lung protective optimal ventilation strategies. This paper presents a machine learning approach for bedside assessment of respiratory resistance (R) and compliance (C). We develop machine learning algorithms to track flow rate and airway pressure and estimate R and C continuously and in real-time. An experimental study is conducted, by connecting a pressure control ventilator to a test lung that simulates various R and C values, to gather sensor data for validation of the devised algorithms. We develop supervised learning algorithms based on decision tree, decision table, and Support Vector Machine (SVM) techniques to predict R and C values. Our experimental results demonstrate that the proposed algorithms achieve 90.3%, 93.1%, and 63.9% accuracy in assessing respiratory R and C using decision table, decision tree, and SVM, respectively. These results along with our ability to estimate R and C with 99.4% accuracy using a linear regression model demonstrate the potential of the proposed approach for constructing a new generation of ventilation technologies that leverage novel computational models to control their underlying parameters for personalized healthcare and context-aware interventions.

published proceedings

  • Annu Int Conf IEEE Eng Med Biol Soc

author list (cited authors)

  • Hezarjaribi, N., Dutta, R., Xing, T., Murdoch, G. K., Mazrouee, S., Mortazavi, B. J., & Ghasemzadeh, H.

citation count

  • 3

complete list of authors

  • Hezarjaribi, Niloofar||Dutta, Rabijit||Xing, Tao||Murdoch, Gordon K||Mazrouee, Sepideh||Mortazavi, Bobak J||Ghasemzadeh, Hassan

publication date

  • July 2018