A labeled guanidine ligand for studying sweet taste. Academic Article uri icon


  • A synthesis of a biotinylated-, coumarin-substituted-N,N'-diarylguanidine 1 is reported. This ligand has structural features conducive to studying sweet taste including a fluorescent tag to facilitate spectroscopic studies of binding to protein-receptors for sweet ligands and an anchor for affinity purification.

published proceedings

  • Bioorg Med Chem Lett

altmetric score

  • 3

author list (cited authors)

  • Feng, Y., Burgess, K., Pledger, D., Cairns, N., & Linthicum, D. S.

citation count

  • 6

complete list of authors

  • Feng, Y||Burgess, K||Pledger, D||Cairns, N||Linthicum, DS

publication date

  • April 1998