Regulation of the Heat-Shock Response in Escherichia coli
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abstract
Cells respond to a sudden increase in temperature by increasing their rate of synthesis of a small number of proteins (reviewed in Neidhardt et al., 1984; Schlesinger et al., 1982). This response is called the heat-shock response, and the proteins synthesized in response to heat stress are called the heat-shock proteins (HSPs). Both prokaryotes and eukaryotes have been shown to have a heat-shock response (Schlesinger et al., 1982). At least two of the HSPs are strongly conserved between prokaryotes and eukaryotes (Bardwell and Craig, 1984), suggesting that the response serves a similar function in all organisms.