SIMULATIONS OF THE HINGE FLOW FIELDS OF A BILEAFLET MECHANICAL HEART VALVE UNDER PHYSIOLOGIC PULSATILE AORTIC CONDITIONS Conference Paper

abstract

• Native heart valves with limited functionality are commonly replaced by prosthetic heart valves. Since the first heart valve replacement in 1960, more than three million valves have been implanted worldwide. The most widely implanted prosthetic heart valve design is currently the bileaflet mechanical heart valve (BMHV), with more than 130,000 implants every year worldwide. However, studies have shown that this valve design can still cause major complications, including hemolysis, platelet activation, and thromboembolic events. Clinical reports and recent in vitro experiments suggest that these thrombogenic complications are associated with the hemodynamic stresses imposed on blood elements by the complex non-physiologic flow induced by the valve, in particular in the hinge region.

name of conference

• ASME 2008 Summer Bioengineering Conference, Parts A and B

authors

• Borazjani, Iman

published proceedings

• PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B

author list (cited authors)

• Simon, H. A., Ge, L., Borazjani, I., Sotiropoulos, F., & Yoganathan, A. P.

citation count

• 0

complete list of authors

• Simon, Helene A||Ge, Liang||Borazjani, Iman||Sotiropoulos, Fotis||Yoganathan, Ajit P

publication date

• January 2009

publisher

• ASME International  Publisher

keywords

• Assistive Technology
• Bioengineering
• Cardiovascular
• Heart Disease
• Rehabilitation

Digital Object Identifier (DOI)

• 10.1115/sbc2008-192939

International Standard Book Number (ISBN) 13

• 978-0-7918-4321-5

start page

• 1093

end page

• 1094

issue

• PART B

URL

• http://dx.doi.org/10.1115/sbc2008-192939