Heparin enhances the rate of binding of fibronectin to collagen. uri icon

abstract

  • 125I-labelled fibronectin is shown to bind to both native and denatured collagen immobilized on Sephadex beads in reactions that exhibit different kinetics. The rates of both reactions were enhanced by the presence of heparin or highly sulphated dextran sulphate but not by other glycosaminoglycans or dextran sulphates having low sulphate contents.

published proceedings

  • Biochem J

author list (cited authors)

  • Johansson, S., & Hk, M.

citation count

  • 115

complete list of authors

  • Johansson, S||Höök, M

publication date

  • January 1980