Phosphinic acid inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme a reductase Academic Article uri icon


  • Compound 3 was designed as a prototype for a new class of phosphorus-based inhibitors of 3-hydorxy-3-methylglutaryl-coenzyme A reductase. The synthesis and biochemical evaluation of compound 3 are described. 1991.

published proceedings

  • Bioorganic & Medicinal Chemistry Letters

author list (cited authors)

  • Dreyer, G. B., Garvie, C. T., Metcalf, B. W., Meek, T. D., & Mayer, R. J.

citation count

  • 4

complete list of authors

  • Dreyer, Geoffrey B||GarvieĀ§, Clare T||Metcalf, Brian W||Meek, Thomas D||Mayer, Ruth J

publication date

  • January 1991