Phosphinic acid inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme a reductase Academic Article

abstract

• Compound 3 was designed as a prototype for a new class of phosphorus-based inhibitors of 3-hydorxy-3-methylglutaryl-coenzyme A reductase. The synthesis and biochemical evaluation of compound 3 are described. 1991.

authors

• Meek, Thomas

published proceedings

• Bioorganic & Medicinal Chemistry Letters

author list (cited authors)

• Dreyer, G. B., Garvie, C. T., Metcalf, B. W., Meek, T. D., & Mayer, R. J.

citation count

• 4

complete list of authors

• Dreyer, Geoffrey B||Garvie§, Clare T||Metcalf, Brian W||Meek, Thomas D||Mayer, Ruth J

publication date

• January 1991

publisher

• Elsevier  Publisher

published in

• Bioorganic and Medicinal Chemistry Letters  Journal

Digital Object Identifier (DOI)

• 10.1016/s0960-894x(01)80788-5

start page

• 151

end page

• 154

volume

• 1

issue

• 3

URL

• http://dx.doi.org/10.1016/s0960-894x(01)80788-5