Analysis of enzyme induction in bacteria Academic Article uri icon

abstract

  • The theoretical relations between the induced initiation and accumulation of lac mRNA and its translation are derived, taking the kinetics of repressor-operator dissociation and enzyme maturation into account. These relations are used to evaluate observed data on lac induction and to estimate a number of parameters that characterize the transcription and translation of the beta-galactosidase gene in the bacterium Escherichia coli B/r growing at three different rates (0.7-2.1 doublings/h).

author list (cited authors)

  • Young, R. y., & Bremer, H.

citation count

  • 13

publication date

  • November 1975