S gene product: identification and membrane localization of a lysis control protein. Academic Article uri icon


  • The product of the bacteriophage S gene has been previously shown to be required for an essential step in triggering host cell lysis. By using two different protein labeling systems, maxicells and UV-irradiated infected cells, we identified the S gene product as an 8,500-molecular-weight polypeptide associated with the cell envelope. The apparent molecular weight is significantly less than the 11,500 predicted from the S gene sequence. We were unable to confirm two previous identifications of S gene products, an acidic 15,000-molecular-weight polypeptide found by two-dimensional gel electrophoresis of infected cells and a 5,500-molecular-weight polypeptide in purified phage particles.

published proceedings

  • J Bacteriol

altmetric score

  • 3

author list (cited authors)

  • Altman, E., Altman, R. K., Garrett, J. M., Grimaila, R. J., & Young, R.

citation count

  • 40

complete list of authors

  • Altman, E||Altman, RK||Garrett, JM||Grimaila, RJ||Young, R

publication date

  • September 1983