3D Core-Shell Simulation of Hydrogel Swelling Behavior for Controlled Drug Delivery Conference Paper uri icon


  • In this paper, a three-dimensional dynamic model describing drug delivery and swelling behavior of polyelectrolyte gels was developed based on the Maxwell-Stefan equation and Bio-heat equation. COMSOL software was employed to simulate hydrogel swelling and the transportation of created automatically by COMSOL, and it had 78035 elements, which was unconcerned with the results. The results showed that Maxwell-Stefan equation and Bio-heat equation were suitable for modeling hydrogel behavior of swelling with temperature change. In addition, when temperature increased, the hydrogel swelling increased which also intensified drug release.

name of conference

  • Volume 3B: Biomedical and Biotechnology Engineering

published proceedings

  • Volume 3B: Biomedical and Biotechnology Engineering

altmetric score

  • 0.25

author list (cited authors)

  • Wang, J., Qiu, J., & Wang, S.

citation count

  • 4

complete list of authors

  • Wang, Jilong||Qiu, Jenny||Wang, Shiren

publication date

  • January 2013