STEREOSELECTIVE ADDITION OF CYANIDE ION TO CHIRAL RHENIUM PI-ALDEHYDE COMPLEXES OF THE FORMULAS [(ETA-5-C5H5)RE(NO)(PPH3)(ETA-2-O=CHR)]+BF4- - A NEW SYNTHESIS OF OPTICALLY-ACTIVE CYANOHYDRIN DERIVATIVES uri icon

abstract

  • Reaction of optically active aldehyde complexes (+)-(RS)-[(5-C5H5)Re(NO)(PPh3)(2-OCHR)]+ BF4- and (CH3CH2)4N+ CN- gives cyanohydrin alkoxide complexes (+)-(5-C5H5)Re(NO)-(PPh3)(OCH(CN)R) (78-95%) of 89-53% de. The alkoxide ligands are then converted to optically active MTPA esters (96-85%) of 90-56% de. 1989.

published proceedings

  • TETRAHEDRON LETTERS

author list (cited authors)

  • GARNER, C. M., FERNANDEZ, J. M., & GLADYSZ, J. A.

citation count

  • 19

complete list of authors

  • GARNER, CM||FERNANDEZ, JM||GLADYSZ, JA

publication date

  • January 1989