False-Positive Reactions in the Immunoprecipitation Test for Meat Identification
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During the course of experiments into the specificity of the ring precipitation test it was found that a commercial anti-porcine serum reacted with bovine plasma. When this phenomenon was investigated it was found to be non-immunological in nature and that plasma obtained from blood treated with calcium chelating agents gave a positive reaction with normal serum. The species of origin of the reactants appeared to have no effect on the reaction. Further analysis indicated that a similar false-positive reaction could be obtained using sodium ascorbate either as an anticoagulant or as an additive to ground beef. Preliminary studies were conducted on the mechanism of this reaction.
author list (cited authors)
TIZARD, I. R., FISH, N. A., & CAOILI, F.