Neurocognitive and behavioral profiles of children with Landau-Kleffner syndrome. Academic Article uri icon


  • This is a retrospective study of 14 cases of children with Landau-Kleffner syndrome (LKS), the most prominent feature of which is acquired aphasia. These children were followed at a tertiary care pediatric epilepsy center. From the research data base, all LKS cases with neuropsychological evaluation were extracted. Children ranged in age from 6 to 13 years (M=9.12; SD=2.19) at the time of assessment (1 to 10 years post-onset). The majority of the children were white males, and all but one continued to experience seizure activity. Global intellectual functioning ranged from 59 to 101 (M=82.07; SD=12.14). Across the 14 cases reviewed, the neuropsychological profiles are considered in the context of neurological and syndrome-related factors. For these cases, 86% demonstrated continued expressive, and 50% had receptive language problems with 57% exhibiting poor auditory processing. Furthermore, 50 to 57% had deficits in auditory working memory and verbal memory. Academically, the majority had poor reading fluency and comprehension; 50% exhibited difficulty with mathematics. Finally, 57% evidenced attentional or other behavioral problems. Better understanding of LKS can assist in targeted assessment and intervention planning.

published proceedings

  • Appl Neuropsychol Child

altmetric score

  • 1.5

author list (cited authors)

  • Riccio, C. A., Vidrine, S. M., Cohen, M. J., Acosta-Cotte, D., & Park, Y.

citation count

  • 6

complete list of authors

  • Riccio, Cynthia A||Vidrine, Stephanie M||Cohen, Morris J||Acosta-Cotte, Delmaris||Park, Yong

publication date

  • October 2017