Landomycin A inhibits DNA synthesis and G1/S cell cycle progression. Academic Article

abstract

• Landomycin A was found to inhibit the uptake of [3H]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent studies showed that landomycin A inhibits cell cycle progression.

authors

• Ramos, Kenneth
• Smith, Roger

published proceedings

• Bioorg Med Chem Lett

author list (cited authors)

• Crow, R. T., Rosenbaum, B., Smith, R., Guo, Y., Ramos, K. S., & Sulikowski, G. A.

citation count

• 58

complete list of authors

• Crow, RT||Rosenbaum, B||Smith, R||Guo, Y||Ramos, KS||Sulikowski, GA

publication date

• January 1999

publisher

• Elsevier  Publisher

published in

• Bioorganic and Medicinal Chemistry Letters  Journal

keywords

• Aminoglycosides
• Animals
• Anti-Bacterial Agents
• Antibiotics, Antineoplastic
• Carbohydrate Sequence
• Cells, Cultured
• DNA Replication
• Flow Cytometry
• G1 Phase
• Mice
• Molecular Sequence Data
• Muscle, Smooth
• S Phase

Digital Object Identifier (DOI)

• 10.1016/s0960-894x(99)00261-9

start page

• 1663

end page

• 1666

volume

• 9

issue

• 12

URL

• http://dx.doi.org/10.1016/s0960-894x(99)00261-9