Krieger, Inna Research Assistant Professor

academic article

• Mellott, D. M., Torres, D., Krieger, I. V., Cameron, S. A., Moghadamchargari, Z., Laganowsky, A., ... Harris, L. D. (2021). Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid. Journal of the American Chemical Society. 
  
• Krieger, I. V., Kuznetsov, V., Chang, J., Zhang, J., Moussa, S. H., Young, R. F., & Sacchettini, J. C. (2020). The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. J Mol Biol.  432(16), 4623-4636.
  
• Brown, E. E., Miller, A. K., Krieger, I. V., Otto, R. M., Sacchettini, J. C., & Herman, J. K. (2019). A DNA-Binding Protein Tunes Septum Placement during Bacillus subtilis Sporulation. J Bacteriol.  201(16), e00287-e00219.
  
• Carey, A. F., Rock, J. M., Krieger, I. V., Chase, M. R., Fernandez-Suarez, M., Gagneux, S., ... Fortune, S. M. (2018). TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. PLOS Pathogens.  14(3), e1006939-e1006939.
  
• Ellenbarger, J. F., Krieger, I. V., Huang, H., Gmez-Coca, S., Ioerger, T. R., Sacchettini, J. C., Wheeler, S. E., & Dunbar, K. R. (2018). Anion- Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. Journal of Chemical Information and Modeling.  58(10), 2085-2091.
  
• Huang, H., Krieger, I. V., Parai, M. K., Gawandi, V. B., & Sacchettini, J. C. (2016). Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. Journal of Biological Chemistry.  291(53), 27421-27432.
  
• Prigozhin, D. M., Krieger, I. V., Huizar, J. P., Mavrici, D., Waldo, G. S., Hung, L., ... Alber, T. (2014). Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. PLoS One.  9(12), e116249-e116249.
  
• Krieger, I. V., Freundlich, J. S., Gawandi, V. B., Roberts, J. P., Gawandi, V. B., Sun, Q., ... Sacchettini, J. C. (2012). Structure-guided discovery of phenyl-diketo acids as potent inhibitors of M. tuberculosis malate synthase. Chemistry and Biology.  19(12), 1556-1567.