Krieger, Inna Research Assistant Professor

academic article

• Singh, V., Grzegorzewicz, A. E., Fienberg, S., Mller, R., Khonde, L. P., Sanz, O., ... Ghorpade, S. R. (2022). 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis. ACS Infectious Diseases.  8(11), 2315-2326.
  
• Kreutzfeldt, K. M., Jansen, R. S., Hartman, T. E., Gouzy, A., Wang, R., Krieger, I. V., ... Ehrt, S. (2022). CinA mediates multidrug tolerance in Mycobacterium tuberculosis. Nature Communications.  13(1), 2203.
  
• Katti, S. S., Krieger, I. V., Poudel, L., Sacchettini, J. S., & Igumenova, T. I. (2022). Mechanism of diacylglycerol sensing revealed by integrative structural biology approach. Biophysical Journal.  121(3), 224A-224A.
  
• Katti, S. S., Krieger, I. V., Ann, J., Lee, J., Sacchettini, J. C., & Igumenova, T. I. (2022). Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nature Communications.  13(1), 2695.
  
• Katti, S. S., Krieger, I. V., Sacchettini, J. C., & Igumenova, T. I. (2022). Structural basis of agonist capture by PKC-regulatory C1 domain. Biophysical Journal.  121(3), 224A-224A.
  
• Mellott, D. M., Torres, D., Krieger, I. V., Cameron, S. A., Moghadamchargari, Z., Laganowsky, A., ... Harris, L. D. (2021). Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid. Journal of the American Chemical Society.  143(42), 17666-17676.
  
• Krieger, I. V., Kuznetsov, V., Chang, J., Zhang, J., Moussa, S. H., Young, R. F., & Sacchettini, J. C. (2020). The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. JOURNAL OF MOLECULAR BIOLOGY.  432(16), 4623-4636.
  
• Brown, E. E., Miller, A. K., Krieger, I. V., Otto, R. M., Sacchettini, J. C., & Herman, J. K. (2019). A DNA-Binding Protein Tunes Septum Placement during Bacillus subtilis Sporulation. Journal of Bacteriology.  201(16), e00287-e00219.
  
• Crutcher, F. K., Moran-Diez, M. E., Krieger, I. V., & Kenerley, C. M. (2019). Effects on hyphal morphology and development by the putative copper radical oxidase glx1 in Trichoderma virens suggest a novel role as a cell wall associated enzyme. 131, 103245-103245.
  
• Rittershaus, E., Baek, S., Krieger, I. V., Nelson, S. J., Cheng, Y., Nambi, S., ... Sassetti, C. M. (2018). A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. Cell Chemical Biology.  25(12), 1495-1505.e3.
  
• Ellenbarger, J. F., Krieger, I. V., Huang, H., Gmez-Coca, S., Ioerger, T. R., Sacchettini, J. C., Wheeler, S. E., & Dunbar, K. R. (2018). Anion- Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. Journal of Chemical Information and Modeling.  58(10), 2085-2091.
  
• Carey, A. F., Rock, J. M., Krieger, I. V., Chase, M. R., Fernandez-Suarez, M., Gagneux, S., ... Fortune, S. M. (2018). TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. PLOS Pathogens.  14(3), e1006939-e1006939.
  
• Huang, H., Krieger, I. V., Parai, M. K., Gawandi, V. B., & Sacchettini, J. C. (2016). Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. Journal of Biological Chemistry.  291(53), 27421-27432.
  
• Prigozhin, D. M., Krieger, I. V., Huizar, J. P., Mavrici, D., Waldo, G. S., Hung, L., ... Alber, T. (2014). Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. PLoS One.  9(12), e116249-e116249.
  
• Krieger, I. V., Freundlich, J. S., Gawandi, V. B., Roberts, J. P., Gawandi, V. B., Sun, Q., ... Sacchettini, J. C. (2012). Structure-guided discovery of phenyl-diketo acids as potent inhibitors of M. tuberculosis malate synthase. Chemistry and Biology.  19(12), 1556-1567.