How Does Membrane Oxidation Affect Cell Delivery and Cell Killing? Academic Article uri icon

abstract

  • The biophysical properties of cellular membranes intimately influence the delivery of cargoes into cells by cell-penetrating peptides (CPPs) and the bactericidal activity of antimicrobial peptides (AMPs). Here, we discuss how lipid oxidation creates important chemical and biophysical changes in membranes, and hypothesize about the observed synergy between oxidized membranes and membrane-active peptides.

published proceedings

  • Trends Biotechnol

altmetric score

  • 4.8

author list (cited authors)

  • Libardo, M., Wang, T., Pellois, J., & Angeles-Boza, A. M.

citation count

  • 17

complete list of authors

  • Libardo, M Daben J||Wang, Ting-Yi||Pellois, Jean-Philippe||Angeles-Boza, Alfredo M

publication date

  • August 2017