HR job title
- Professor
- Contact Info
Neuman, Benjamin Professor
Positions
- Professor, Biology, College of Arts and Sciences
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Overview
Publications
selected publications
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academic article
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Alwine, J., Goodrum, F., Banfield, B., Bloom, D., Britt, W. J., Broadbent, A. J., ... Yurochko, A.
(2024).
The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence. Journal of Virology.
e0124024.
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Khatua, K., Alugubelli, Y. R., Yang, K. S., Vulupala, V. R., Blankenship, L. R., Coleman, D., ... Liu, W. R.
(2024).
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors. 225, 105874-105874.
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Alugubelli, Y. R., Xiao, J., Khatua, K., Kumar, S., Sun, L., Ma, Y., ... Xu, S.
(2024).
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of Medicinal Chemistry.
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Alugubelli, Y. R., Xiao, J., Khatua, K., Kumar, S., Ma, Y., Ma, X. R., ... Xu, S.
(2023).
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. 4(10-06), 2023.09.29.560163.
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Woo, P., de Groot, R. J., Haagmans, B., Lau, S., Neuman, B. W., Perlman, S., ... Yeh, S.
(2023).
ICTV Virus Taxonomy Profile: Coronaviridae 2023. JOURNAL OF GENERAL VIROLOGY.
104(4),
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Chaki, S. P., Kahl-McDonagh, M. M., Neuman, B. W., & Zuelke, K. A.
(2022).
Receptor-Binding-Motif-Targeted Sanger Sequencing: a Quick and Cost-Effective Strategy for Molecular Surveillance of SARS-CoV-2 Variants. Microbiology spectrum.
10(3), e0066522-e00622.
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Rajil, N., Esmaeili, S., Neuman, B. W., Nessler, R., Wu, H., Yi, Z., ... Scully, M. O.
(2022).
Quantum optical immunoassay: upconversion nanoparticle-based neutralizing assay for COVID-19. Scientific Reports.
12(1), 1263.
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Cao, W., Cho, C., Geng, Z. Z., Shaabani, N., Ma, X. R., Vatansever, E. C., ... Liu, W. R.
(2022).
Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay. ACS Central Science.
8(2), 192-204.
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Rajil, N., Sokolov, A., Yi, Z., Adams, G., Agarwal, G., Belousov, V., ... Scully, M.
(2021).
A fiber optic-nanophotonic approach to the detection of antibodies and viral particles of COVID-19. Nanophotonics.
10(1), 235-246.
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Neuman, B. W., Brashear, W. A., Brun, M., Chaki, S. P., Fischer, R., Guidry, S. J., ... Zuelke, K.
(2021).
Case Report: Paucisymptomatic College-Age Population as a Reservoir for Potentially Neutralization-Resistant Severe Acute Respiratory Syndrome Coronavirus 2 Variants. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE.
105(5), 1227-1229.
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Storey, N., Rabiey, M., Neuman, B. W., Jackson, R. W., & Mulley, G.
(2020).
Genomic Characterisation of Mushroom Pathogenic Pseudomonads and Their Interaction with Bacteriophages. Viruses.
12(11), 1286-1286.
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Ramirez, M., Neuman, B. W., & Ramirez, C. A.
(2020).
Bacteriophages as promising agents for the biological control of Moko disease (Ralstonia solanacearum) of banana. Biological Control.
149, 104238-104238.
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Alsaadi, E., Neuman, B. W., & Jones, I. M.
(2020).
Identification of a Membrane Binding Peptide in the Envelope Protein of MHV Coronavirus. Viruses.
12(9), 1054-1054.
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Peng, T., Liu, X., Adams, L. G., Agarwal, G., Akey, B., Cirillo, J., ... Scully, M.
(2020).
Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2. Applied Physics Letters.
117(12), 120601-120601.
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James, S. L., Rabiey, M., Neuman, B. W., Percival, G., & Jackson, R. W.
(2020).
Isolation, Characterisation and Experimental Evolution of Phage that Infect the Horse Chestnut Tree Pathogen, Pseudomonas syringae pv. aesculi. Current Microbiology.
77(8), 1438-1447.
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Coronaviridae Study Group of the International Committee on Taxonomy of Viruses.
(2020).
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology.
5(4), 536-544.
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Alsaadi, E., Neuman, B. W., & Jones, I. M.
(2019).
A Fusion Peptide in the Spike Protein of MERS Coronavirus. Viruses.
11(9), 825-825.
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Bukhari, K., Mulley, G., Gulyaeva, A. A., Zhao, L., Shu, G., Jiang, J., & Neuman, B. W.
(2018).
Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus. Virology.
524, 160-171.
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Cobb, A., Dell'Isola, A., Abdulsattar, B. O., McLachlan, M., Neuman, B. W., Mueller, C., ... Elvidge, W.
(2018).
Synthesis and antiviral activity of novel spirocyclic nucleosides. New Journal of Chemistry.
42(22), 18363-18380.
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Doyle, N., Neuman, B. W., Simpson, J., Hawes, P. C., Mantell, J., Verkade, P., Alrashedi, H., & Maier, H. J.
(2018).
Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane Pairing. Viruses.
10(9), 477-477.
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Whittaker, G. R., Andr, N. M., & Millet, J. K.
(2018).
Improving Virus Taxonomy by Recontextualizing Sequence-Based Classification with Biologically Relevant Data: the Case of the Alphacoronavirus 1 Species. mSphere.
3(1), e00463-e00417.
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Mller, C., Hardt, M., Schwudke, D., Neuman, B. W., Pleschka, S., & Ziebuhr, J.
(2018).
Inhibition of Cytosolic Phospholipase A2 Impairs an Early Step of Coronavirus Replication in Cell Culture. 92(4), e01463-e01417.
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Neuman, B. W.
(2016).
Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles. ANTIVIRAL RESEARCH.
135, 97-107.
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Zeng, C., Wu, A., Wang, Y. i., Xu, S., Tang, Y., Jin, X. u., ... Guo, D.
(2016).
Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales. 90(15), 6675-6685.
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Maier, H. J., Neuman, B. W., Bickerton, E., Keep, S. M., Alrashedi, H., Hall, R., & Britton, P.
(2016).
Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity. Scientific Reports.
6(1), 27126.
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Dent, S. D., Xia, D., Wastling, J. M., Neuman, B. W., Britton, P., & Maier, H. J.
(2015).
The proteome of the infectious bronchitis virus Beau-R virion. JOURNAL OF GENERAL VIROLOGY.
96(12), 3499-3506.
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Kiss, G., Bouchet-Marquis, C., Pullan, L., Keene, D., & Neuman, B. W.
(2015).
New CLEM Method to Reveal Ultrastructural Reorganization in the Host Cell during Coronavirus Infection. 21(S3), 537-538.
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V'kovski, P., Al-Mulla, H., Thiel, V., & Neuman, B. W.
(2015).
New insights on the role of paired membrane structures in coronavirus replication. Virus Research.
202, 33-40.
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Dell'Isola, A., McLachlan, M., Neuman, B. W., AlMullah, H., Binks, A., Elvidge, W., Shankland, K., & Cobb, A.
(2015).
ChemInform Abstract: Synthesis and Antiviral Properties of Spirocyclic [1,2,3]Triazolooxazine Nucleosides. 46(10), no-no.
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Iftikhar, Y., Jackson, R., & Neuman, B. W.
(2015).
DETECTION OF TOBACCO MOSAIC TOBAMOVIRUS IN CIGARETTES THROUGH RT-PCR. PAKISTAN JOURNAL OF AGRICULTURAL SCIENCES.
52(3), 667-670.
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Neuman, B. W., Chamberlain, P., Bowden, F., & Joseph, J.
(2014).
Atlas of coronavirus replicase structure. Virus Research.
194, 49-66.
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Neuman, B. W., Angelini, M. M., & Buchmeier, M. J.
(2014).
Does form meet function in the coronavirus replicative organelle?. TRENDS IN MICROBIOLOGY.
22(11), 642-647.
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Dell'Isola, A., McLachlan, M., Neuman, B. W., Al-Mullah, H., Binks, A., Elvidge, W., Shankland, K., & Cobb, A.
(2014).
Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides. Chemistry - A European Journal.
20(37), 11685-11689.
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Al-Mulla, H., Turrell, L., Smith, N. M., Payne, L., Baliji, S., Zst, R., ... Neuman, B. W.
(2014).
Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. 5(2), e01107-e01113.
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Angelini, M. M., Neuman, B. W., & Buchmeier, M. J.
(2014).
Untangling membrane rearrangement in the nidovirales. DNA and Cell Biology.
33(3), 122-127.
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Neuman, B. W.
(2013).
How the double spherules of infectious bronchitis virus impact our understanding of RNA virus replicative organelles. mBio.
4(6), e00987-e00913.
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Schley, D., Whittaker, R. J., & Neuman, B. W.
(2013).
Arenavirus budding resulting from viral-protein-associated cell membrane curvature. Journal of the Royal Society Interface.
10(86), 20130403-20130403.
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Angelini, M. M., Akhlaghpour, M., Neuman, B. W., & Buchmeier, M. J.
(2013).
Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles. mBio.
4(4), e00524-e00513.
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Neuman, B. W., Kiss, G., Al-Mulla, H., Dokland, T., Buchmeier, M. J., Weikl, T., & Schley, D.
(2013).
Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacement. PLoS ONE.
8(2), e57916-e57916.
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Neuman, B. W., Bederka, L. H., Stein, D. A., Ting, J., Moulton, H. M., & Buchmeier, M. J.
(2011).
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. 55(10), 4631-4638.
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Neuman, B. W., Kiss, G., Kunding, A. H., Bhella, D., Baksh, M. F., Connelly, S., ... Buchmeier, M. J.
(2011).
A structural analysis of M protein in coronavirus assembly and morphology. Journal of Structural Biology.
174(1), 11-22.
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Zst, R., Cervantes-Barragan, L., Habjan, M., Maier, R., Neuman, B. W., Ziebuhr, J., ... Thiel, V.
(2011).
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nature Immunology.
12(2), 137-143.
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Johnson, M. A., Chatterjee, A., Neuman, B. W., & Wthrich, K.
(2010).
SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding. Journal of Molecular Biology.
400(4), 724-742.
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Serrano, P., Johnson, M. A., Chatterjee, A., Neuman, B. W., Joseph, J. S., Buchmeier, M. J., Kuhn, P., & Wthrich, K.
(2009).
Nuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3. Journal of Virology.
83(24), 12998-13008.
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Chatterjee, A., Johnson, M. A., Serrano, P., Pedrini, B., Joseph, J. S., Neuman, B. W., ... Wuthrich, K.
(2009).
Nuclear Magnetic Resonance Structure Shows that the Severe Acute Respiratory Syndrome Coronavirus-Unique Domain Contains a Macrodomain Fold. Journal of Virology.
83(4), 1823-1836.
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Neuman, B. W., Joseph, J. S., Saikatendu, K. S., Serrano, P., Chatterjee, A., Johnson, M. A., ... Kuhn, P.
(2008).
Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3. Journal of Virology.
82(11), 5279-5294.
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Moulton, H. M., Fletcher, S., Neuman, B. W., McClorey, G., Stein, D. A., Abes, S., ... Iversen, P. L.
(2007).
Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. 35(Pt 4), 826-828.
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Serrano, P., Johnson, M. A., Almeida, M. S., Horst, R., Herrmann, T., Joseph, J. S., ... Wthrich, K.
(2007).
Nuclear Magnetic Resonance Structure of the N-Terminal Domain of Nonstructural Protein 3 from the Severe Acute Respiratory Syndrome Coronavirus. Journal of Virology.
81(21), 12049-12060.
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Burrer, R., Neuman, B. W., Ting, J., Stein, D. A., Moulton, H. M., Iversen, P. L., Kuhn, P., & Buchmeier, M. J.
(2007).
Antiviral Effects of Antisense Morpholino Oligomers in Murine Coronavirus Infection Models. Journal of Virology.
81(11), 5637-5648.
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Joseph, J. S., Saikatendu, K. S., Subramanian, V., Neuman, B. W., Buchmeier, M. J., Stevens, R. C., & Kuhn, P.
(2007).
Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch. Journal of Virology.
81(12), 6700-6708.
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Saunders, A. A., Ting, J., Meisner, J., Neuman, B. W., Perez, M., de la Torre, J. C., & Buchmeier, M. J.
(2007).
Mapping the Landscape of the Lymphocytic Choriomeningitis Virus Stable Signal Peptide Reveals Novel Functional Domains. Journal of Virology.
81(11), 5649-5657.
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Saikatendu, K. S., Joseph, J. S., Subramanian, V., Neuman, B. W., Buchmeier, M. J., Stevens, R. C., & Kuhn, P.
(2007).
Ribonucleocapsid Formation of Severe Acute Respiratory Syndrome Coronavirus through Molecular Action of the N-Terminal Domain of N Protein. Journal of Virology.
81(8), 3913-3921.
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Joseph, J. S., Saikatendu, K. S., Subramanian, V., Neuman, B. W., Brooun, A., Griffith, M., ... Kuhn, P.
(2006).
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs. Journal of Virology.
80(16), 7894-7901.
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Neuman, B. W., Adair, B. D., Yoshioka, C., Quispe, J. D., Orca, G., Kuhn, P., ... Buchmeier, M. J.
(2006).
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy. Journal of Virology.
80(16), 7918-7928.
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Saikatendu, K. S., Joseph, J. S., Subramanian, V., Clayton, T., Griffith, M., Moy, K., ... Kuhn, P.
(2005).
Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3. Structure.
13(11), 1665-1675.
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Peti, W., Johnson, M. A., Herrmann, T., Neuman, B. W., Buchmeier, M. J., Nelson, M., ... Wthrich, K.
(2005).
Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7. 79(20), 12905-12913.
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Joseph, J., Brooun, A., Neuman, B., Abola, E., Stevens, J., Saikatendu, K., ... Wilson, I.
(2005).
Functional and structural proteomics of SARS: defining a rational response to emerging diseases. Acta Crystallographica Section A: Foundations of Crystallography.
61(a1), c25-c25.
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Neuman, B. W., Stein, D. A., Kroeker, A. D., Churchill, M. J., Kim, A. M., Kuhn, P., ... Buchmeier, M. J.
(2005).
Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers. 79(15), 9665-9676.
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Neuman, B. W., Adair, B. D., Burns, J. W., Milligan, R. A., Buchmeier, M. J., & Yeager, M.
(2005).
Complementarity in the supramolecular design of arenaviruses and retroviruses revealed by electron cryomicroscopy and image analysis. 79(6), 3822-3830.
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Sampath, R., Hofstadler, S. A., Blyn, L. B., Eshoo, M. W., Hall, T. A., Massire, C., ... Ecker, D. J.
(2005).
Rapid identification of emerging pathogens: coronavirus. Emerging Infectious Diseases.
11(3), 373-379.
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Neuman, B. W., Stein, D. A., Kroeker, A. D., Paulino, A. D., Moulton, H. M., Iversen, P. L., & Buchmeier, M. J.
(2004).
Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth. 78(11), 5891-5899.
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Blankenship, L. R., Yang, K. S., Vulupala, V. R., Alugubelli, Y. R., Khatua, K., Coleman, D., ... Liu, W. R.
SARS-CoV2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme. ACS Medicinal Chemistry Letters.
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Alwine, J., Goodrum, F., Banfield, B., Bloom, D., Britt, W. J., Broadbent, A. J., ... Yurochko, A.
(2024).
The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence. Journal of Virology.
e0124024.
-
chapter
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Johnson, M. A., Chatterjee, A., Neuman, B. W., & Wthrich, K.
(2021).
SARS Coronavirus Unique Domain: Three-Domain Molecular Architecture in Solution and RNA Binding. NMR with Biological Macromolecules in Solution.
(pp. 155-173).
World Scientific Publishing.
-
Neuman, B. W., & Buchmeier, M. J.
(2016).
Supramolecular Architecture of the Coronavirus Particle. Advances in virus research.
ADVANCES IN VIRUS RESEARCH, VOL 96: CORONAVIRUSES.
(pp. 1-27).
Elsevier.
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Dent, S., & Neuman, B. W.
(2015).
Purification of coronavirus virions for Cryo-EM and proteomic analysis. Methods in molecular biology (Clifton, N.J.).
CORONAVIRUSES: METHODS AND PROTOCOLS.
(pp. 99-108).
Springer Nature.
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Neuman, B. W., Adair, B. D., Yeager, M., & Buchmeier, M. J.
(2008).
Purification and electron cryomicroscopy of coronavirus particles. Methods in molecular biology (Clifton, N.J.).
SARS- and Other Coronaviruses.
(pp. 129-136).
Springer Nature.
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Neuman, B. W.
(2007).
Supramolecular Architecture of the Coronavirus Particle. Nidoviruses.
(pp. 201-210).
American Society for Microbiology.
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Neuman, B. W., Stein, D. A., Kroeker, A. D., Moulton, H. M., Bestwick, R. K., Iversen, P. L., & Buchmeier, M. J.
(2006).
Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers. Advances in Experimental Medicine and Biology.
The Nidoviruses.
(pp. 567-571).
Springer Nature.
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Neuman, B. W., Adair, B. D., Yoshioka, C., Quispe, J. D., Milligan, R. A., Yeager, M., & Buchmeier, M. J.
(2006).
Ultrastructure of SARS-CoV, FIPV, and MHV revealed by electron cryomicroscopy. Advances in Experimental Medicine and Biology.
The Nidoviruses.
(pp. 181-185).
Springer Nature.
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Britton, P., Stirrups, K., Dalton, K., Shaw, K., Evans, S., Neuman, B., ... Cavanagh, D.
(2001).
Use of an infectious bronchitis virus D-RNA as an RNA vector. Advances in Experimental Medicine and Biology.
The Nidoviruses.
(pp. 507-512).
Springer Nature.
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Neuman, B., Cavanagh, D., & Britton, P.
(2001).
Use of defective RNAs containing reporter genes to investigate targeted recombination for avian infectious bronchitis virus. Advances in Experimental Medicine and Biology.
The Nidoviruses.
(pp. 513-518).
Springer Nature.
-
Johnson, M. A., Chatterjee, A., Neuman, B. W., & Wthrich, K.
(2021).
SARS Coronavirus Unique Domain: Three-Domain Molecular Architecture in Solution and RNA Binding. NMR with Biological Macromolecules in Solution.
(pp. 155-173).
World Scientific Publishing.
-
institutional repository document
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Khatua, K., Alugubelli, Y. R., Yang, K. S., Vulupala, V. R., Blankenship, L. R., Coleman, D. D., ... Liu, W. R.
(2023).
An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease
-
Rajil, N., Esmaeili, S., Neuman, B. W., Nessler, R., Wu, H., Yi, Z., ... Scully, M. O.
(2021).
Quantum Optical Immunoassay: Upconversion Nanoparticle-based Neutralizing Assay for COVID-19
-
Gorbalenya, A. E., Baker, S. C., Baric, R. S., de Groot, R. J., Drosten, C., Gulyaeva, A. A., ... Ziebuhr, J.
(2020).
Severe acute respiratory syndrome-related coronavirus: The species and its viruses a statement of the Coronavirus Study Group
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Alrashedi, H., Jones, I., Mulley, G., & Neuman, B. W.
(2017).
Bioinformatics analysis for L polymerase homology of arenaviruses
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Khatua, K., Alugubelli, Y. R., Yang, K. S., Vulupala, V. R., Blankenship, L. R., Coleman, D. D., ... Liu, W. R.
(2023).
An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease
Teaching
teaching activities
- BIOL100 Horizons In Biology Instructor
- BIOL291 Research Instructor
- BIOL443 Early Stgs Anim Evol Instructor
- BIOL445 Biology Of Viruses Instructor
- BIOL451 Bioinformatics Instructor
- BIOL491 Hnr-research Instructor
- BIOL685 Directed Studies Instructor
- BIOL689 Sptp: Biology Of Viruses Instructor
- BIOL691 Research Instructor
Background
education and training
- Ph.D. in Virology, University of Reading - (Reading, United Kingdom) 2001
- B.S. in Biology, University of Toledo - (Toledo, Ohio, United States) 1997
- Scripps Research Institute - (San Diego, California, United States) , Postdoctoral Training 2004
Contact
first name
- Benjamin
has last name
- Neuman
Other
In the News
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- Rising share of coronavirus tests coming back positive in Texas fuels fears of another wave News Release
- Scientists battle over the ultimate origin story: Where did the coronavirus come from? News Release
- What You Need To Know About The Delta COVID-19 Variant News Release
- bneuman@tamu.edu