Changes in Bone Mineral Density and Mechanical Properties Due to Alcohol and Ovariectomy in Trabecular Bone of Female Rats Conference Paper

abstract

• Alcohol consumption is a known risk factor exacerbating postmenopausal osteoporosis [1,2]. The current study was undertaken to investigate these effects using the rat animal model. Recent studies with rats have shown deleterious effects due to alcohol [3,4], but no significant effects when combined estrogen deficiency induced by ovariectomy (OVX) [5]. This last study did not report mechanical properties, however. The objective of the current study was to investigate the effects of alcohol and OVX on trabecular bone mechanical properties and bone mineral density (BMD) in adult female rats. An important issue in evaluating osteoporosis and related bone maladies clinically is the relation between bone mineral density (BMD) and fracture risk or incidence. Thus, an additional goal of the current study was to examine the relationships (correlations) between trabecular bone BMD and mechanical properties.

name of conference

• Advances in Bioengineering

authors

• Hogan, Harry

published proceedings

• Advances in Bioengineering

author list (cited authors)

• Hogan, H. A., & Sampson, H. W.

citation count

• 0

complete list of authors

• Hogan, Harry A||Sampson, H Wayne

publication date

• January 2002

publisher

• ASME International  Publisher

keywords

• 2 Aetiology
• 2.1 Biological And Endogenous Factors
• 3 Good Health And Well Being
• 32 Biomedical And Clinical Sciences
• 3202 Clinical Sciences
• Aging
• Alcoholism, Alcohol Use And Health
• Estrogen
• Musculoskeletal
• Osteoporosis
• Substance Misuse

Digital Object Identifier (DOI)

• 10.1115/imece2002-32598

International Standard Book Number (ISBN) 10

• 0791836509

International Standard Book Number (ISBN) 13

• 9780791836507

start page

• 305

end page

• 306

URL

• http://dx.doi.org/10.1115/imece2002-32598

user-defined tag

• 3 Good Health and Well-Being