The purpose of this chapter is to analyze the relationship between change in attitude toward computers and overall course satisfaction of participants. Of the 262 randomly selected participants, 64% completed the study. Data were collected using questionnaires and course satisfaction rating survey. Results of the study indicated that there was a statistically significant difference in overall course satisfaction between the e-learning group (the treatment group) and the traditional group (control group). The traditional group was more satisfied with their course than the treatment group on the general program construct and the overall course satisfaction index. Results of the t-tests indicated that overall the e-learning group liked computers more than the traditional group prior to treatment and remained with this attitude after treatment. The control group had a statistically significant change in attitude toward computers after the treatment to reflect a less favorable attitude toward computers after the treatment.