Serial serum pancreatic lipase immunoreactivity concentrations in a dog with histologically confirmed pancreatitis
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Objective: Serial measurement of serum pancreatic lipase immunoreactivity (cPLI) concentration in a dog with histologically confirmed pancreatitis. Materials and methods: A 15-year-old male castrated Lhasa Apso was presented for chronic vomiting. Results: Following clinical and laboratory evaluation with unspecific results gastroscopy revealed a pyloric mass, which was removed by a Billroth-I procedure. A few days after surgery the dog deteriorated further displaying recurrent vomiting. Based on clinical evaluation, abdominal ultrasound, and serum cPLI concentration pancreatitis was diagnosed. Therapy slowly led to clinical improvement of the patient and a decreasing serum cPLI concentration. Unfortunately, the dog suddenly developed neurological signs and the owner decided to have the animal euthanized. Pancreatitis was confirmed on histopathology. Conclusion: Serial measurement of serum cPLI concentration can be used to monitor progression of pancreatitis in dogs. Clinical relevance: Monitoring the progression of canine pancreatitis can be challenging. This is the first report of using serial serum cPLI concentrations for monitoring the progression of pancreatitis in a clinical patient.