Relationships between low serum cobalamin concentrations and methlymalonic acidemia in cats. Academic Article

abstract

• BACKGROUND: Serum cobalamin concentrations below reference range are a common consequence of gastrointestinal disease in cats. Serum cobalamin 867 nmol/L. Sensitivity and specificity of serum cobalamin concentrations 867 nmol/L were analyzed using a receiver-operator characteristic curve. RESULTS: There was a negative correlation between serum cobalamin and MMA concentrations (Spearman's r=-0.74, P < 0.0001). The prevalence of MMA >or= 867 nmol/L in cats with serum cobalamin 867 nmol/L. No significant difference in serum folate concentrations was detected between affected and unaffected cats. CONCLUSIONS AND CLINICAL IMPORTANCE: Elevated MMA concentrations, suggesting cobalamin deficiency, are common in cats with serum cobalamin

authors

• Steiner, Joerg

published proceedings

• J Vet Intern Med

author list (cited authors)

• Ruaux, C. G., Steiner, J. M., & Williams, D. A.

citation count

• 36

complete list of authors

• Ruaux, CG||Steiner, JM||Williams, DA

publication date

• May 2009

publisher

• Wiley  Publisher

published in

• Journal of Veterinary Internal Medicine (JVIM)  Journal

keywords

• Animals
• Cat Diseases
• Cats
• Methylmalonic Acid
• Retrospective Studies
• Sensitivity And Specificity
• Vitamin B 12
• Vitamin B 12 Deficiency

PubMed Central ID

• 19422473

Digital Object Identifier (DOI)

• 10.1111/j.1939-1676.2009.0308.x

start page

• 472

end page

• 475

volume

• 23

issue

• 3

URL

• http://dx.doi.org/10.1111/j.1939-1676.2009.0308.x