Relationships between Low Serum Cobalamin Concentrations and Methlymalonic Acidemia in Cats Academic Article uri icon

abstract

  • BACKGROUND: Serum cobalamin concentrations below reference range are a common consequence of gastrointestinal disease in cats. Serum cobalamin 867 nmol/L. Sensitivity and specificity of serum cobalamin concentrations 867 nmol/L were analyzed using a receiver-operator characteristic curve. RESULTS: There was a negative correlation between serum cobalamin and MMA concentrations (Spearman's r=-0.74, P < 0.0001). The prevalence of MMA >or= 867 nmol/L in cats with serum cobalamin 867 nmol/L. No significant difference in serum folate concentrations was detected between affected and unaffected cats. CONCLUSIONS AND CLINICAL IMPORTANCE: Elevated MMA concentrations, suggesting cobalamin deficiency, are common in cats with serum cobalamin

author list (cited authors)

  • Ruaux, C. G., Steiner, J. M., & Williams, D. A.

citation count

  • 30

publication date

  • April 2009

publisher