selected publications academic article Smith, D. L., Li, C., Matecic, M., Maqani, N., Bryk, M., & Smith, J. S (2009). Calorie restriction effects on silencing and recombination at the yeast rDNA. Aging Cell. 8(6), 633-642. Li, C., Mueller, J. E., Elfline, M., & Bryk, M (2008). Linker histone H1 represses recombination at the ribosomal DNA locus in the budding yeast Saccharomyces cerevisiae. Molecular Microbiology. Mueller, J. E., & Bryk, M (2007). Isw1 acts independently of the Isw1a and Isw1b complexes in regulating transcriptional silencing at the ribosomal DNA locus in Saccharomyces cerevisiae. J Mol Biol. Mueller, J. E., Li, C., & Bryk, M (2007). Isw2 regulates gene silencing at the ribosomal DNA locus in Saccharomyces cerevisiae. Biochem Biophys Res Commun. Mueller, J. E., Canze, M., & Bryk, M (2006). The requirements for COMPASS and Paf1 in transcriptional silencing and methylation of histone H3 in Saccharomyces cerevisiae. GENETICS. Bryk, M., Briggs, S. D., Strahl, B. D., Curcio, M. J., Allis, C. D., & Winston, F (2002). Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae by a Sir2-independent mechanism. Curr Biol. Briggs, S. D., Bryk, M., Strahl, B. D., Cheung, W. L., Davie, J. K., Dent, S. Y., Winston, F., & Allis, C. D (2001). Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. GENES & DEVELOPMENT. Bryk, M., Banerjee, M., Conte, D., & Curcio, M. J (2001). The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays. Mol Cell Biol. Bryk, M., Belisle, M., Mueller, J. E., & Belfort, M (1995). Selection of a remote cleavage site by I-tevI, the td intron-encoded endonuclease. J Mol Biol. Bell-Pedersen, D., Quirk, S. M., Bryk, M., & Belfort, M (1991). I-TevI, the endonuclease encoded by the mobile td intron, recognizes binding and cleavage domains on its DNA target. Proceedings of the National Academy of Sciences of USA. Bryk, M., & Belfort, M (1990). Spontaneous shuffling of domains between introns of phage T4. Nature.
principal investigator on REU Site - Summer Undergraduate Research Program in Biochemistry awarded by Directorate for Biological Sciences - (Arlington, Virginia, United States) 2020 - 2023 Studies to understand the formation and function of chromatin in highly repeated DNA sequences in eukaryotes. awarded by National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States) 2016 - 2021
co-principal investigator on REU Site: Summer Undergraduate Research Program in Biochemistry awarded by National Science Foundation - (Arlington, Virginia, United States) 2014 - 2020 REU Site: Summer Undergraduate Research Program In Biochemistry awarded by National Science Foundation - (Arlington, Virginia, United States) 2009 - 2015
teaching activities BICH101 Perspectives In Bich And Gene Instructor BICH431 Molecular Genetics Instructor BICH491 Hnr-research Instructor BICH631 Biochemical Genetics Instructor BICH673 Gene Expression Instructor BICH681 Seminar Instructor BICH685 Directed Studies Instructor BICH691 Research Instructor BICH697 Teaching Biochem Labs Instructor GENE101 Perspectives In Bich And Gene Instructor GENE302 Principles Of Genetics Instructor GENE431 Molecular Genetics Instructor GENE491 Hnr-research Instructor GENE673 Gene Expression Instructor GENE691 Research Instructor
chaired theses and dissertations Huning, Laura Elizabeth (2020-08). Transcriptional Activation of Eukaryotic Promoters via Zinc Finger Protein 143. Jordan, Rachel Alison (2015-12). Epigenetic Regulation of Silent Chromatin in Saccharomyces cerevisiae. Leehy, Katherine (2013-08). Dissection of the telomere complex CST in Arabidopsis thaliana. Li, Chonghua (2008-12). The role of histones and histone modifying enzymes in ribosomal dna silencing in saccharomyces cerevisiae. Williamson, Kelly M. (2011-05). The Role of Chromatin Structure and Histone Modifications in Gene Silencing at the Ribosomal DNA Locus in Saccharomyces cerevisiae.
education and training Ph.D., Albany Medical Center Hospital - (Albany, New York, United States) 1994 M.S., Albany Medical Center Hospital - (Albany, New York, United States) 1991 Wadsworth Center - (Albany, New York, United States) , Postdoctoral Training 1997
mailing address Texas A&M University Biochemistry & Biophysics 2128 TAMU College Station, TX 77843-2128 USA