Microtubule shuttles on kinesin-coated glass micro-wire tracks. Academic Article

abstract

• Gliding of microtubule filaments on surfaces coated with the motor protein kinesin has potential applications for nano-scale devices. The ability to guide the gliding direction in three dimensions allows the fabrication of tracks of arbitrary geometry in space. Here, we achieve this by using kinesin-coated glass wires of micrometer diameter range. Unlike previous methods in which the guiding tracks are fixed on flat two-dimensional surfaces, the flexibility of glass wires in shape and size facilitates building in-vitro devices that have deformable tracks.

authors

• Hwang, Wonmuk
• Teizer, Winfried

published proceedings

• Biomed Microdevices

author list (cited authors)

• Kim, K., Liao, A. L., Sikora, A., Oliveira, D., Nakazawa, H., Umetsu, M., ... Teizer, W.

citation count

• 7

complete list of authors

• Kim, Kyongwan||Liao, Andrew L||Sikora, Aurélien||Oliveira, Daniel||Nakazawa, Hikaru||Umetsu, Mitsuo||Kumagai, Izumi||Adschiri, Tadafumi||Hwang, Wonmuk||Teizer, Winfried

publication date

• January 2014

publisher

• Springer Nature  Publisher

published in

• Biomedical Microdevices  Journal

keywords

• Glass
• Kinesins
• Microscopy, Fluorescence
• Microtubules

PubMed Central ID

• 24737133

Digital Object Identifier (DOI)

• 10.1007/s10544-014-9852-6

start page

• 501

end page

• 508

volume

• 16

issue

• 4

URL

• http%3A%2F%2Fdx.doi.org%2F10.1007%2Fs10544-014-9852-6