Microtubule shuttles on kinesin-coated glass micro-wire tracks
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Gliding of microtubule filaments on surfaces coated with the motor protein kinesin has potential applications for nano-scale devices. The ability to guide the gliding direction in three dimensions allows the fabrication of tracks of arbitrary geometry in space. Here, we achieve this by using kinesin-coated glass wires of micrometer diameter range. Unlike previous methods in which the guiding tracks are fixed on flat two-dimensional surfaces, the flexibility of glass wires in shape and size facilitates building in-vitro devices that have deformable tracks.
author list (cited authors)
Kim, K., Liao, A. L., Sikora, A., Oliveira, D., Nakazawa, H., Umetsu, M., ... Teizer, W.