Microtubule shuttles on kinesin-coated glass micro-wire tracks Academic Article uri icon

abstract

  • Gliding of microtubule filaments on surfaces coated with the motor protein kinesin has potential applications for nano-scale devices. The ability to guide the gliding direction in three dimensions allows the fabrication of tracks of arbitrary geometry in space. Here, we achieve this by using kinesin-coated glass wires of micrometer diameter range. Unlike previous methods in which the guiding tracks are fixed on flat two-dimensional surfaces, the flexibility of glass wires in shape and size facilitates building in-vitro devices that have deformable tracks.

author list (cited authors)

  • Kim, K., Liao, A. L., Sikora, A., Oliveira, D., Nakazawa, H., Umetsu, M., ... Teizer, W.

citation count

  • 5

publication date

  • April 2014