The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives. Academic Article uri icon


  • Using evolved pyrrolysyl-tRNA synthetase-tRNA(CUA)(Pyl) pairs, L-phenylalanine, p-iodo-L-phenylalanine and p-bromo-L-phenylalanine have been genetically incorporated into proteins at amber mutation sites in E. coli.

published proceedings

  • Mol Biosyst

altmetric score

  • 3.5

author list (cited authors)

  • Wang, Y., Russell, W. K., Wang, Z., Wan, W., Dodd, L. E., Pai, P., Russell, D. H., & Liu, W. R.

citation count

  • 70

complete list of authors

  • Wang, Yane-Shih||Russell, William K||Wang, Zhiyong||Wan, Wei||Dodd, Lindsey E||Pai, Pei-Jing||Russell, David H||Liu, Wenshe R

publication date

  • March 2011