Thermomorphic fluorous phosphines as organocatalysts for Michael addition reactions Academic Article uri icon

abstract

  • The fluorous phosphines P[(CH2)mRfn]3 (Rfn = (CF2) n-1CF3; m/n = 2/8, 3/8, 3/10) are efficient nucleophilic catalysts of Michael addition reactions. They can be easily recycled based upon their highly temperature-dependent solubilities (thermomorphism), with recovery by simple liquid/solid phase separation. The phosphonium salt formed by reaction of the nucleophilic phosphine with the α,β-unsaturated system appears to be a significant component of the catalyst rest state. © 2010 Elsevier Ltd. All rights reserved.

altmetric score

  • 3

author list (cited authors)

  • Gimbert, C., Vallribera, A., Gladysz, J. A., & Jurisch, M.

citation count

  • 7

publication date

  • September 2010