An Unexpected Role of Carbon Disulfide: A New and Efficient Method for the Synthesis of 2‐Substituted Benzimidazoles Academic Article uri icon


  • © 2014 Verlag Helvetica Chimica Acta AG, Zürich. A new and efficient methodology for the synthesis of 2-substituted benzimidazoles is described. In this procedure, CS2 unexpectedly facilitated the cyclization reaction between benzene-1,2-diamine and benzenecarbaldehydes in CH2Cl2 at room temperature. The reactions occur under mild conditions require simpler equipment and easier workup procedures.

author list (cited authors)

  • Gladysz, J. A., Safaei, H. R., & Nouri, S.

citation count

  • 9

publication date

  • November 2014