Tris(1,2-diphenylethylenediamine)cobalt(III) Complexes: Chiral Hydrogen Bond Donor Catalysts for Enantioselective -Aminations of 1,3-Dicarbonyl Compounds. Academic Article

abstract

• The enantiopure salt -[Co((S,S)-dpen)3](3+)2Cl(-)B(C6F5)4(-) is an effective hydrogen bond donor catalyst for additions of 1,3-dicarbonyl compounds to di-tert-butyl azodicarboxylate in the presence of N-methylmorpholine (1.0:1.0:0.10) in CH3CN at 0 C, as illustrated with educts derived from five- or six-membered ring ketones (99-88% yields, >99-91% ee) and cycloheptanone (94%, 72% ee) as well as 2-cyanocyclopentanone (92%, 45% ee) and an acyclic system (98%, >99% ee).

authors

• Gladysz, John

published proceedings

• Org Lett

altmetric score

• 0.5

author list (cited authors)

• Kumar, A., Ghosh, S. K., & Gladysz, J. A.

citation count

• 53

complete list of authors

• Kumar, Anil||Ghosh, Subrata K||Gladysz, John A

publication date

• February 2016

publisher

• American Chemical Society (ACS)  Publisher

published in

• Organic Letters  Journal

keywords

• 0302 Inorganic Chemistry

PubMed Central ID

• 26820242

Digital Object Identifier (DOI)

• 10.1021/acs.orglett.6b00023

start page

• 760

end page

• 763

volume

• 18

issue

• 4

URL

• http%3A%2F%2Fdx.doi.org%2F10.1021%2Facs.orglett.6b00023