ASYMMETRIC-SYNTHESIS OF ORGANOMETALLIC REAGENTS USING ENZYMATIC METHODS Academic Article

abstract

• The use of enzymatic catalysis in the synthesis and resolution of organometallic complexes is reviewed and discussed. Examples show the potential of biological catalysts for oxidation, reduction, hydrolysis, and esterification of both transition metal and main group organometallic substrates. Chirality in organometallic complexes caused by the presence of chiral carbon centers in substituent groups, tetrahedral or pseudotetrahedral metal centers, and planes of asymmetry can all be recognized by whole cell or isolated enzyme catalysts. Biocatalysts that achieve high levels of kinetic resolution are described. Other catalysts that produce high levels of asymmetric induction in reactions of a prochiral substrate are also described. 1992 Humana Press Inc.

authors

• Bergbreiter, David

published proceedings

• APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

author list (cited authors)

• BERGBREITER, D. E., & MOMONGAN, M.

citation count

• 9

complete list of authors

• BERGBREITER, DE||MOMONGAN, M

publication date

• January 1992

publisher

• Springer Nature  Publisher

published in

• Applied Biochemistry and Biotechnology  Journal

keywords

• Catalysis
• Enzymatic Lipase Dehydrogenase
• Enzyme Resolution
• Organometallic Synthesis Resolution

Digital Object Identifier (DOI)

• 10.1007/BF02922148

start page

• 55

end page

• 72

volume

• 32

issue

• 1-3

URL

• http%3A%2F%2Fdx.doi.org%2F10.1007%2Fbf02922148