ELECTROPHILIC ASYMMETRIC SYNTHESES OF ALPHA-HYDROXY CARBOXYLIC-ACIDS Academic Article uri icon

abstract

  • Asymmetric electrophilic synthesis of -hydroxy carboxylic acids from chiral amide derivatives of tert-butyl- and trialkylsilyl- protected glycolic and lactic acids are described which lead to chiral -hydroxy carboxylic acids in 60-95% diastereomic excess. 1986.

published proceedings

  • TETRAHEDRON LETTERS

altmetric score

  • 3

author list (cited authors)

  • LUDWIG, J. W., NEWCOMB, M., & BERGBREITER, D. E.

citation count

  • 22

complete list of authors

  • LUDWIG, JW||NEWCOMB, M||BERGBREITER, DE

publication date

  • January 1986