Lesions of the caudate nucleus selectively impair "reference memory" acquisition in the radial maze. Academic Article uri icon

abstract

  • Groups of Long-Evans rats with bilateral lesions of the caudate nucleus, sham lesions, or no lesions were given one trial per day in an eight-arm radial maze. The same four maze arms were baited on each trial. The remaining four arms never contained food. Optimal performance required animals to enter each of the baited arms only once on each trial and to avoid entering the arms in the unbaited set. Rats with caudate lesions learned to enter each of the baited arms only once on each trial. However, these rats were severely impaired in learning to avoid entering the arms in the unbaited set. Implications for dual-memory theories are discussed.

published proceedings

  • Behav Neural Biol

altmetric score

  • 3

author list (cited authors)

  • Packard, M. G., & White, N. M.

citation count

  • 92

complete list of authors

  • Packard, MG||White, NM

publication date

  • January 1990