selected publications academicarticle Shaikh, R., Larson, N. J., Hanjaya-Putra, D., Zartman, J., Umulis, D. M., Li, L., & Reeves, G. T. (2024). Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway Bandodkar, P., Shaikh, R., & Reeves, G. T. (2023). ISRES+: an improved evolutionary strategy for function minimization to estimate the free parameters of systems biology models. Bioinformatics. 39(7), btad403. McArthur, N., Cruz-Teran, C., Thatavarty, A., Reeves, G. T., & Rao, B. M. (2022). Experimental and Analytical Framework for "Mix-and-Read" Assays Based on Split Luciferase. ACS Omega. 7(28), 24551-24560. Bowen, J., Schloop, A. E., Reeves, G. T., Menegatti, S., & Rao, B. M. (2020). Discovery of Membrane-Permeating Cyclic Peptides via mRNA Display. Bioconjugate Chemistry. 31(10), 2325-2338. Schloop, A. E., Carrell-Noel, S., Friedman, J., Thomas, A., & Reeves, G. T. (2020). Mechanism and implications of morphogen shuttling: Lessons learned from dorsal and Cactus in Drosophila. Developmental Biology. 461(1), 13-18. Al Asafen, H., Bandodkar, P. U., Carrell-Noel, S., Schloop, A. E., Friedman, J., & Reeves, G. T. (2020). Robustness of the Dorsal morphogen gradient with respect to morphogen dosage. PLoS Computational Biology. 16(4), e1007750-e1007750. Reeves, G., Bandodkar, P., & Asafen, H. A. (2020). Spatiotemporal control of gene expression boundaries using a feedforward loop. 34(S1), 1-1. Bandodkar, P. U., Al Asafen, H., & Reeves, G. T. (2020). Spatiotemporal control of gene expression boundaries using a feedforward loop. Developmental Dynamics. 249(3), 369-382. Jacobsen, T., Yi, G., Al Asafen, H., Jermusyk, A. A., Beisel, C. L., & Reeves, G. T. (2020). Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems. PLoS ONE. 15(4), e0232046-e0232046. Reeves, G. T. (2019). The engineering principles of combining a transcriptional incoherent feedforward loop with negative feedback. Journal of Biological Engineering. 13(1), 62. Asafen, H. A., Bandodkar, P. U., Carrell-Noel, S., & Reeves, G. T. (2019). Robustness of the Dorsal morphogen gradient with respect to morphogen dosage. 739292. Jermusyk, A. A., Gharavi, S. E., Tingare, A. S., & Reeves, G. T. (2018). Determination of novel members in the Drosophila melanogaster anteriorposterior patterning system using natural variation. 319434. Asafen, H. A., Clark, N. M., Jacobsen, T., Sozzani, R., & Reeves, G. T. (2018). Dorsal/NF-B exhibits a dorsal-to-ventral mobility gradient in the Drosophila embryo. 320754. Carrell, S. N., O'Connell, M. D., Jacobsen, T., Pomeroy, A. E., Hayes, S. M., & Reeves, G. T. (2017). A facilitated diffusion mechanism establishes the Drosophila Dorsal gradient. Development. 144(23), 4450-4461. Jermusyk, A. A., Murphy, N. P., & Reeves, G. T. (2016). Analyzing negative feedback using a synthetic gene network expressed in the Drosophila melanogaster embryo. BMC Systems Biology. 10(1), 85. Reeves, G. T., & Hrischuk, C. E. (2016). Survey of Engineering Models for Systems Biology. Computational Biology Journal. 2016, 1-12. O'Connell, M. D., & Reeves, G. T. (2015). The presence of nuclear cactus in the early Drosophila embryo may extend the dynamic range of the dorsal gradient. PLoS Computational Biology. 11(4), e1004159-e1004159. Carrell, S. N., & Reeves, G. T. (2015). Imaging the dorsal-ventral axis of live and fixed Drosophila melanogaster embryos. Methods in molecular biology (Clifton, N.J.). 1189, 63-78. Garcia, M., Nahmad, M., Reeves, G. T., & Stathopoulos, A. (2013). Size-dependent regulation of dorsal-ventral patterning in the early Drosophila embryo. Developmental Biology. 381(1), 286-299. Trisnadi, N., Altinok, A., Stathopoulos, A., & Reeves, G. T. (2013). Image analysis and empirical modeling of gene and protein expression. Methods. 62(1), 68-78. Reeves, G. T., Trisnadi, N., Truong, T. V., Nahmad, M., Katz, S., & Stathopoulos, A. (2012). Dorsal-ventral gene expression in the Drosophila embryo reflects the dynamics and precision of the dorsal nuclear gradient. Developmental Cell. 22(3), 544-557. Nahmad, M., Reeves, G., & Stathopoulos, A. (2011). Size-dependent regulation of dorsal-ventral patterning in the early Drosophila embryo. Developmental Biology. 356(1), 119-119. McMahon, A., Reeves, G. T., Supatto, W., & Stathopoulos, A. (2010). Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity. Development. 137(13), 2167-2175. Liberman, L. M., Reeves, G. T., & Stathopoulos, A. (2009). Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 106(52), 22317-22322. Reeves, G. T., & Stathopoulos, A. (2009). Graded dorsal and differential gene regulation in the Drosophila embryo. Cold Spring Harbor Perspectives in Biology. 1(4), a000836-a000836. Reeves, G. T., & Fraser, S. E. (2009). Biological systems from an engineer's point of view. PLoS Biology. 7(1), e21-35. Reeves, G. T., Muratov, C. B., Schpbach, T., & Shvartsman, S. Y. (2006). Quantitative models of developmental pattern formation. Developmental Cell. 11(3), 289-300. Goentoro, L. A., Reeves, G. T., Kowal, C. P., Martinelli, L., Schpbach, T., & Shvartsman, S. Y. (2006). Quantifying the Gurken morphogen gradient in Drosophila oogenesis. Developmental Cell. 11(2), 263-272. Reeves, G. T., Kalifa, R., Klein, D. E., Lemmon, M. A., & Shvartsman, S. Y. (2005). Computational analysis of EGFR inhibition by Argos. Developmental Biology. 284(2), 523-535. Pilyugin, S. S., Reeves, G. T., & Narang, A. (2004). Predicting stability of mixed microbial cultures from single species experiments: 1. Phenomenological model. Mathematical Biosciences. 192(2), 85-109. Pilyugin, S. S., Reeves, G. T., & Narang, A. (2004). Predicting stability of mixed microbial cultures from single species experiments: 2. Physiological model. Mathematical Biosciences. 192(2), 111-136. Klein, D. E., Nappi, V. M., Reeves, G. T., Shvartsman, S. Y., & Lemmon, M. A. (2004). Argos inhibits epidermal growth factor receptor signalling by ligand sequestration. Nature. 430(7003), 1040-1044. Reeves, G. T., Narang, A., & Pilyugin, S. S. (2004). Growth of mixed cultures on mixtures of substitutable substrates: the operating diagram for a structured model. Journal of Theoretical Biology. 226(2), 143-157. Shoemaker, J., Reeves, G. T., Gupta, S., Pilyugin, S. S., Egli, T., & Narang, A. (2003). The dynamics of single-substrate continuous cultures: the role of transport enzymes. Journal of Theoretical Biology. 222(3), 307-322. Al Asafen, H., Beseli, A., Chen, H., Hiremath, S., Williams, C. M., & Reeves, G. T. Dynamics of BMP signaling and stable gene expression in the early Drosophila embryo. Biology Open. 13(9), bio061646. Shaikh, R., Larson, N. J., Kam, J., Hanjaya-Putra, D., Zartman, J., Umulis, D. M., Li, L., & Reeves, G. T. Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathway. npj Systems Biology and Applications. 10(1), 103. chapter Schloop, A. E., Bandodkar, P. U., & Reeves, G. T. (2020). Formation, interpretation, and regulation of the Drosophila Dorsal/NF-B gradient. Current Topics in Developmental Biology. Small, S., & Briscoe, J. (Eds.), GRADIENTS AND TISSUE PATTERNING. (pp. 143-191). Elsevier. Jermusyk, A. A., & Reeves, G. T. (2016). Transcription Factor Networks. Encyclopedia of Cell Biology. (pp. 232-241). Elsevier. Jermusyk, A. A., & Reeves, G. T. (2016). Transcription Factor Networks. Encyclopedia of Cell Biology. (pp. 63-71). Elsevier. institutional repository document Schloop, A. E., Hiremath, S., Shaikh, R., Williams, C. M., & Reeves, G. T. (2024). Spatiotemporal dynamics of NF-B/Dorsal inhibitor IB/Cactus in Drosophila blastoderm embryos Bandodkar, P. U., Shaikh, R. R., & Reeves, G. T. (2023). ISRES+: An improved evolutionary strategy for function minimization to estimate the free parameters of Systems Biology models Asafen, H., Beseli, A., Hiremath, S., Williams, C. M., & Reeves, G. T. (2022). Dynamics of BMP signaling in the early Drosophila embryo McArthur, N., Cruz-Teran, C., Thatavarty, A., Reeves, G. T., & Rao, B. M. (2022). Experimental and analytical framework for mix-and-read assays based on split luciferase Bowen, J., Schloop, A. E., Reeves, G. T., Menegatti, S., & Rao, B. M. (2020). Discovery of membrane-permeating cyclic peptides via mRNA display Bandodkar, P. U., Asafen, H. A., & Reeves, G. T. (2019). Spatiotemporal control of gene expression boundaries using a feedforward loop Schloop, A. E., Carrell-Noel, S., & Reeves, G. T. (2019). Shuttling of Dorsal by Cactus: mechanism and implications Jacobsen, T., Yi, G., Asafen, H. A., Jermusyk, A. A., Beisel, C. L., & Reeves, G. T. (2019). Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems Carrell, S. N., OConnell, M. D., Allen, A. E., Smith, S. M., & Reeves, G. T. (2016). A Facilitated Diffusion Mechanism Establishes the Drosophila Dorsal Gradient Dima, S. S., & Reeves, G. T. Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition Shaikh, R., & Reeves, G. T. Elucidating the role of multiple feedback loops in regulating stem cell decisions
teaching activities CHEN205 Chem Engr Thermo I Instructor CHEN291 Hnr-research Instructor CHEN320 Chen Analysis Instructor CHEN461 Process Dynamics & Cntrl Instructor CHEN489 Sptp: Eng Principles Of Cell Instructor CHEN491 Hnr-research Instructor CHEN689 Sptp:eng Principles Of Cell Instructor CHEN691 Research Instructor GENE691 Research Instructor
education and training Ph.D. in Chemical Engineering, Princeton University - (Princeton, New Jersey, United States) 2008 B.S. in Mathematics, University of Florida - (Gainesville, Florida, United States) 2002
awards and honors Faculty Early Career Development (CAREER) Program, conferred by National Science Foundation - (Arlington, Virginia, United States), 2013