My scientific research, graduate and post-graduate programs employs multi-disciplinary approaches to conduct and study use of naturally occurring germplasm for crop improvement. Elements of the research include wild-species germplasm introgression, chromosome substitution, reproductive and ploidy manipulations, conventional cytogenetics and fluorescence in situ hybridization, genetic analysis, DNA marker and assay (SNP) development, marker assisted selection, reproductive cytology and genetics, and various types of genome mapping, sequencing, and their integration for genome sequencing and assembly. Most of my research aims to enhance the germplasm, knowledge, science and technologies for genetic improvement Upland cotton, e.g., economic yield and sustainability; some, however, is devoted to sorghum and peanut, especially wide hybridization and germplasm utilization.