American Society of Hematology Publisher

publisher of

• A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities 2023
• Mechanisms and Therapeutic Strategies to Reverse TET2 Mutant Clonal Hematopoiesis and the Risk of MDS, AML, and Atherosclerotic Cardiovascular Disease.  Blood.  142:937-937. 2023
• Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells..  Blood.  142:1056-1070. 2023
• A Circulating Microbial Metabolite Drives the Clonal Expansion of Pre-Leukemic Cells.  Blood.  140:975-976. 2022
• Prediction of Outcome in Hospitalized Patients with COVID-19: Development of a COVID-19 Scoring Prognostic Model.  Blood.  140:11224-11225. 2022
• Inflammasome activation promotes venous thrombosis through pyroptosis..  Blood Advances.  5:2619-2623. 2021
• Minimal Role for the Alternative Pathway in Complement Activation By HIT Immune Complexes.  Blood.  138:2076-2076. 2021
• Targeting the Oncogenic Functions of an RNA-Binding Protein Involved in Hematologic Malignancies.  Blood.  138:2226-2226. 2021
• OvCa-Chip microsystem recreates vascular endothelium-mediated platelet extravasation in ovarian cancer..  Blood Advances.  4:3329-3342. 2020
• Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis..  Blood.  135:845-856. 2020
• Engineering a Hematopoietic Stem Cell Niche By Revitalizing Mesenchymal Stem Cells with Five Transcription Factors.  Blood.  134:5004-5004. 2019
• Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis.  Blood.  134:3644-3644. 2019
• L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling..  Blood.  134:1445-1457. 2019
• A Combination Strategy Targeting Enhancer Plasticity Exerts Synergistic Lethality Against Beti-Resistant Leukemia Cells.  Blood.  134:5053-5053. 2019
• Longitudinal Sensitivity of the MD Anderson Symptom Inventory for Acute Myeloid Leukemia.  Blood.  132:4825-4825. 2018
• Mechanisms of establishment and functional significance of DNA demethylation during erythroid differentiation. 2018
• A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury.  Blood.  128:3835-3835. 2016
• Arf6 controls platelet spreading and clot retraction via integrin IIb3 trafficking..  Blood.  127:1459-1467. 2016
• Use of Mathematical Modelling Indicates That Patients Treated for Acute Myeloid Leukaemia (AML) Are Undertreated When Ideal Body Weight Is Used to Dose Chemotherapy.  Blood.  126:4522-4522. 2015
• Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense..  Blood.  126:2047-2058. 2015
• Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis..  Blood.  126:1224-1233. 2015
• Myeloma cell-derived Runx2 promotes myeloma progression in bone..  Blood.  125:3598-3608. 2015
• Impaired Platelet Responses to Thromboxane a2 and Thrombin in Mice Lacking Receptor-Interacting Protein Kinase 3.  Blood.  124:2762-2762. 2014
• VPS33B, a Member of the Sec1/Munc18 Protein Family, Binds to Integrin Beta Subunits and Is Required for IIb3 Outside-in Signaling.  Blood.  124:340-340. 2014
• A critical role for Lyn kinase in strengthening endothelial integrity and barrier function..  Blood.  122:4140-4149. 2013
• Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program..  Blood.  121:4529-4540. 2013
• Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia..  Blood.  121:1783-1794. 2013
• Myelopoiesis is regulated by osteocytes through Gs-dependent signaling..  Blood.  121:930-939. 2013
• Platelets Protect From Lipopolysaccharide-Induced Lethal Endotoxemia by Inhibiting Macrophage-Dependent Inflammation Via the Cyclooxygenase 1 (COX1) Signaling Pathway.  Blood.  120:93-93. 2012
• Response: yes, cGMP plays a stimulatory role in platelet activation.  Blood.  119:5336-5337. 2012
• DISTINCT ROLES for Rap1b In PLATELET SECRETION and INTEGRIN aIIBb3 OUTSIDE-In SIGNALING.  Blood.  118:2200-2200. 2011
• Src Family Kinases Contribute to GI and Gq-Mediated Platelet Activation.  Blood.  118:5263-5263. 2011
• The Longitudinal Relationship Between Inflammatory Markers and Patient-Reported Symptom Severity During Induction Therapy for Multiple Myeloma.  Blood.  118:4920-4920. 2011
• Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A..  Blood.  118:3932-3941. 2011
• Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation..  Blood.  118:3670-3679. 2011
• Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-B signaling in resident macrophages..  Blood.  118:330-338. 2011
• Platelets to hemostasis and beyond..  Blood.  117:3703-3704. 2011
• Pharmaceutical inhibition of glycogen synthetase kinase-3 reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model..  Blood.  117:1641-1651. 2011
• Significant Changes in Inducible Cytokine Synthesis by Activated Peripheral Blood Leukocytes of Multiple Myeloma Patients Receiving Standard Dose Autologous Stem Cell Transplantation.  Blood.  118:5096-5096. 2011
• Concordance Between the Serum Levels of Interleukin-6, Microrna-21, and the Severity of Subjective Symptoms of Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation.  Blood.  116:2953-2953. 2010
• Epigenomic Profiling of Myeloproliferative Diseases Reveal Idiopathic Myelofibrosis as An Epigenetically Distinct Subgroup and Highlights the Epigenetic Effects of Jak2V617F Mutation.  Blood.  116:627-627. 2010
• Preliminary Evidences of Circulating Inflammatory Markers Associated with Symptom Development In Patients with Multiple Myeloma During Induction Therapy.  Blood.  116:4734-4734. 2010
• A novel P2Y12-Independent Signaling Pathway Mediating Akt Phosphorylation In Response to Thrombin Receptors.  Blood.  116:3191-3191. 2010
• Biphasic Roles for the Soluble Guanylyl Cyclase (sGC) In Platelet Activation In Mice.  Blood.  116:486-486. 2010
• The Transient Receptor-Potential Channel 6 Plays a Critical Role In Platelet Function.  Blood.  116:3201-3201. 2010
• Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3..  Blood.  115:4071-4082. 2010
• Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis..  Blood.  115:2449-2457. 2010
• Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1..  Blood.  115:418-429. 2010
• Deficiency of MnSOD in Hematopoietic Stem Cells Causes a Sideroblastic Anemia-Like Phenotype..  Blood.  114:1991-1991. 2009
• Heightened Susceptibility to Influenza Mortality in Immunodeficient Mice Caused by a T-Cell Specific Defect in SOD2..  Blood.  114:1655-1655. 2009
• Heparanase Promotes Osteolysis by Upregulating RANKL A Novel Role for Heparanase in Multiple Myeloma..  Blood.  114:2821-2821. 2009
• Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices..  Blood.  114:237-247. 2009
• Investigation of the Anti-Platelet Activity of a Novel Function-Blocking Antibody Targeting the Human Thromboxane A2 Receptor Protein..  Blood.  114:4019-4019. 2009
• The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice..  Blood.  113:816-826. 2009
• Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway..  Blood.  113:893-901. 2009
• Heparanase Promotes the Osteolytic Phenotype in Multiple Myeloma.  Blood.  112:841-841. 2008
• NMR Structure of a Disulfide-Crosslinked IIb3 Cytoplasmic Domain Heterodimer.  Blood.  112:2866-2866. 2008
• Parathyroid Hormones (PTH) Serum Variations Are Associated with Bortezomib Response in Multiple Myeloma Patients.  Blood.  112:2783-2783. 2008
• Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway..  Blood.  112:1139-1146. 2008
• MM-induced osteolysis: partners in crime..  Blood.  112:3-4. 2008
• The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy..  Blood.  110:2041-2048. 2007
• Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions..  Blood.  109:3147-3151. 2007
• Advances in myeloma therapy: breaking the cycle.  Blood.  109:1798-1798. 2007
• MSCs roll into the mainstream.  Blood.  108:3626-3627. 2006
• A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice..  Blood.  107:2153-2161. 2006
• Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3..  Blood.  107:965-972. 2006
• Differential Mapping of the Amino Acids Mediating Agonist and Antagonist Coordination with the Human Thromboxane A2 Receptor Protein..  Blood.  106:3571-3571. 2005
• The Role of the cGMP-Dependent Protein Kinase II in Platelet Activation and In Vivo Thrombosis..  Blood.  106:653-653. 2005
• Heparanase promotes the spontaneous metastasis of myeloma cells to bone..  Blood.  105:1303-1309. 2005
• Ex Vivo Blockade of NF-[dappa]B Signaling in Alloreactive T Cells Prevents Murine Graft-Versus-Host Disease (GVHD)..  Blood.  104:3058-3058. 2004
• Keratinocyte Growth Factor Ameliorates Acute Graft-versus-Host Disease in a Novel Nonmyeloablative Haploidentical Transplantation Model..  Blood.  104:3060-3060. 2004
• Use of Plasma RNA for Real-Time Quantitative RT-PCR to Monitor Imatinib Therapy in Patients with Chronic Myeloid Leukemia..  Blood.  104:1099-1099. 2004
• On the roles of cGMP and glycoprotein Ib in platelet activation. 2004
• Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential..  Blood.  103:1662-1668. 2004
• Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes..  Blood.  103:1647-1652. 2004
• Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs..  Blood.  102:4393-4398. 2003
• A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans..  Blood.  101:4423-4429. 2003
• Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells..  Blood.  99:3692-3701. 2002
• Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta..  Blood.  97:1227-1231. 2001
• Human immunodeficiency virus type 1 Vpr alters bone marrow cell function..  Blood.  93:1906-1915. 1999
• Shiga toxin type 1 activates tumor necrosis factor-alpha gene transcription and nuclear translocation of the transcriptional activators nuclear factor-kappaB and activator protein-1..  Blood.  92:558-566. 1998
• Shiga Toxin Type 1 Activates Tumor Necrosis Factor- Gene Transcription and Nuclear Translocation of the Transcriptional Activators Nuclear Factor-B and Activator Protein-1.  Blood.  92:558-566. 1998
• Heterotypic adherence between human B-lymphoblastic and pre-B-lymphoblastic cells and marrow stromal cells is a biphasic event: integrin very late antigen-4 alpha mediates only the early phase of the heterotypic adhesion..  Blood.  85:168-178. 1995
• The c-kit receptor ligand functions as a mast cell chemoattractant..  Blood.  79:958-963. 1992
• IMMUNOGLOBULIN PHENOTYPE ON B-CELLS CORRELATES WITH CLINICAL STAGE OF CHRONIC LYMPHOCYTIC-LEUKEMIA.  Blood.  62:256-263. 1983
• Immunoglobulin phenotype on B cells correlates with clinical stage of chronic lymphocytic leukemia..  Blood.  62:256-263. 1983
• DETECTION OF TUMOR-CELLS IN THE PERIPHERAL-BLOOD OF NON-LEUKEMIC PATIENTS WITH B-CELL LYMPHOMA - ANALYSIS OF CLONAL EXCESS.  Blood.  55:792-801. 1980
• Detection of tumor cells in the peripheral blood of nonleukemic patients with B-cell lymphoma: analysis of "clonal excess"..  Blood.  55:792-801. 1980
• Drug Rediscovery: Glybenclamide Exhibits Thromboxane Receptor-Dependent Antithrombotic Activity..  Blood.  114:2994-2994.
• Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation.  Blood. 4516-4516. 2016
• Re-Mineralization of Large Pelvic Lytic Lesions By CT Imaging in Patients with Multiple Myeloma: The Arkansas Experience.  Blood. 4193-4193. 2015
• The Role of Adipocyte Lineage Cells in Myeloma Growth and Dissemination in Bone.  Blood. 1797-1797. 2015
• Baseline Symptoms, Female Sex, and Younger Age Are Correlated with Higher Levels of Peri-Collection Pain, Symptoms, and Persistent Discomfort One Year after Related Donor BM and PBSC Donation: An Analysis of the Related Donor Safety Study (RDSafe).  Blood. 3847-3847. 2014
• Heparanase Promotes Myeloma Metastasis By Inducing EMT-like Features in Both Myeloma Cells and Endothelial Cells.  Blood. 2025-2025. 2014
• Optimized Patient- and Leukemia-Specific Chemotherapy Protocols For The Treatment Of Acute Myeloid Leukemia.  Blood. 4227-4227. 2013
• PedsQL (TM) Sickle Cell Disease Module: Feasibility, Reliability and Validity.  Blood. 476-476. 2012
• A high-density MicroRNA array for analyzing the expression of 15,090 verified and predicted small, non-coding RNAs..  Blood. 132B-132B. 2006
• Heparanase promotes the spontaneous metastasis of myeloma cells to bone..  Blood. 183A-184A. 2004
• Increased non-canonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes.  Blood. 882A-883A. 2004