Jose, Jiney (2006-12). Water-soluble benzophenoxazine dyes: syntheses, derivatization and photophysical studies. Master's Thesis. Thesis uri icon

abstract

  • A set of three benzophenoxazine dyes, two completely soluble and one partially soluble in aqueous media, has been prepared and their spectroscopic properties examined. These dyes can be used as either donor or acceptor in synthesis of through-bond energy transfer cassettes. Structural modifications prevented aggregation in water and improved their fluorescence properties in water. Their absorption and emission were studied in both organic and aqueous media. Two of the three dyes have superior quantum yields in aqueous media as compared to other reported dyes. Improved quantum yield makes these dyes attractive candidates for biological studies in aqueous media. We have also prepared alkynes and iodo derivatives of benzophenoxazines, which can be used for synthesis of water-soluble, through-bond, energy transfer cassettes. Alkynes were prepared via Sonogashira coupling.
  • A set of three benzophenoxazine dyes, two completely soluble and one partially soluble
    in aqueous media, has been prepared and their spectroscopic properties examined. These
    dyes can be used as either donor or acceptor in synthesis of through-bond energy transfer
    cassettes. Structural modifications prevented aggregation in water and improved their
    fluorescence properties in water. Their absorption and emission were studied in both
    organic and aqueous media. Two of the three dyes have superior quantum yields in
    aqueous media as compared to other reported dyes. Improved quantum yield makes these
    dyes attractive candidates for biological studies in aqueous media.
    We have also prepared alkynes and iodo derivatives of benzophenoxazines, which can be
    used for synthesis of water-soluble, through-bond, energy transfer cassettes. Alkynes
    were prepared via Sonogashira coupling.

publication date

  • December 2006